Entity Details

Primary name GUC1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP43080
EntryNameGUC1A_HUMAN
FullNameGuanylyl cyclase-activating protein 1
TaxID9606
Evidenceevidence at protein level
Length201
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0001917 photoreceptor inner segment
GO:0005509 calcium ion binding
GO:0007165 signal transduction
GO:0007601 visual perception
GO:0007602 phototransduction
GO:0008048 calcium sensitive guanylate cyclase activator activity
GO:0010753 positive regulation of cGMP-mediated signaling
GO:0022400 regulation of rhodopsin mediated signaling pathway
GO:0030249 guanylate cyclase regulator activity
GO:0031284 positive regulation of guanylate cyclase activity
GO:0071277 cellular response to calcium ion
GO:0097381 photoreceptor disc membrane
GO:0120199 cone photoreceptor outer segment

Subcellular Location

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Subcellular Location
Cell projection
Membrane
Photoreceptor inner segment

Domains

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DomainNameCategoryType
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR028846 Recoverin familyFamilyFamily
IPR033022 Guanylyl cyclase-activating protein 1FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB08231 Myristic acidDrugbanksmall molecule