Entity Details

Primary name 5HT5A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP47898
EntryName5HT5A_HUMAN
FullName5-hydroxytryptamine receptor 5A
TaxID9606
Evidenceevidence at transcript level
Length357
SequenceStatuscomplete
DateCreated1996-02-01
DateModified2021-06-02

Ontological Relatives

GenesHTR5A

GO terms

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GOName
GO:0004993 G protein-coupled serotonin receptor activity
GO:0005791 rough endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0019933 cAMP-mediated signaling
GO:0021766 hippocampus development
GO:0030425 dendrite
GO:0030594 neurotransmitter receptor activity
GO:0032355 response to estradiol
GO:0043204 perikaryon
GO:0051378 serotonin binding
GO:0099060 integral component of postsynaptic specialization membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001397 5-Hydroxytryptamine 5A receptorFamilyFamily
IPR002231 5-hydroxytryptamine receptor familyFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB00246 ZiprasidoneDrugbanksmall molecule
DB00408 LoxapineDrugbanksmall molecule
DB01238 AripiprazoleDrugbanksmall molecule
DB06216 AsenapineDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
5HT5A_HUMANBUD31_HUMANBioGRID, MINT28298427 details