Entity Details

Primary name CPT1A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP50416
EntryNameCPT1A_HUMAN
FullNameCarnitine O-palmitoyltransferase 1, liver isoform
TaxID9606
Evidenceevidence at protein level
Length773
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCPT1A

GO terms

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GOName
GO:0001676 long-chain fatty acid metabolic process
GO:0004095 carnitine O-palmitoyltransferase activity
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0006006 glucose metabolic process
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0006641 triglyceride metabolic process
GO:0006853 carnitine shuttle
GO:0009437 carnitine metabolic process
GO:0010883 regulation of lipid storage
GO:0014070 response to organic cyclic compound
GO:0016020 membrane
GO:0030855 epithelial cell differentiation
GO:0031307 integral component of mitochondrial outer membrane
GO:0031667 response to nutrient levels
GO:0032000 positive regulation of fatty acid beta-oxidation
GO:0042493 response to drug
GO:0042755 eating behavior
GO:0042802 identical protein binding
GO:0043279 response to alkaloid
GO:0045471 response to ethanol
GO:0046677 response to antibiotic
GO:0050796 regulation of insulin secretion
GO:0071398 cellular response to fatty acid
GO:0097421 liver regeneration
GO:1904772 response to tetrachloromethane
GO:1990698 palmitoleoyltransferase activity

Subcellular Location

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Subcellular Location
Mitochondrion outer membrane

Domains

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DomainNameCategoryType
IPR000542 Acyltransferase ChoActase/COT/CPTFamilyFamily
IPR032476 Carnitine O-palmitoyltransferase, N-terminalDomainDomain
IPR039551 Choline/carnitine acyltransferase domainDomainDomain
IPR042231 Choline/Carnitine o-acyltransferase, domain 2FamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00583 LevocarnitineDrugbanksmall molecule
DB01016 GlyburideDrugbanksmall molecule
DB01074 PerhexilineDrugbanksmall molecule