Entity Details

Primary name CP2J2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP51589
EntryNameCP2J2_HUMAN
FullNameCytochrome P450 2J2
TaxID9606
Evidenceevidence at protein level
Length502
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCYP2J2

GO terms

Show/Hide Table
GOName
GO:0005506 iron ion binding
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0006082 organic acid metabolic process
GO:0006631 fatty acid metabolic process
GO:0006690 icosanoid metabolic process
GO:0006805 xenobiotic metabolic process
GO:0008016 regulation of heart contraction
GO:0008392 arachidonic acid epoxygenase activity
GO:0008395 steroid hydroxylase activity
GO:0008404 arachidonic acid 14,15-epoxygenase activity
GO:0008405 arachidonic acid 11,12-epoxygenase activity
GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0016853 isomerase activity
GO:0019373 epoxygenase P450 pathway
GO:0020037 heme binding
GO:0042738 exogenous drug catabolic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043651 linoleic acid metabolic process
GO:0070062 extracellular exosome
GO:0071614 linoleic acid epoxygenase activity
GO:0106255 hydroperoxy icosatetraenoate isomerase activity
GO:0106301 arachidonic acid 5,6-epoxygenase activity

Subcellular Location

Show/Hide Table
Subcellular Location
Endoplasmic reticulum membrane
Microsome membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR001128 Cytochrome P450FamilyFamily
IPR002401 Cytochrome P450, E-class, group IFamilyFamily
IPR008071 Cytochrome P450, E-class, group I, CYP2J-likeFamilyFamily
IPR017972 Cytochrome P450, conserved siteSiteConserved site
IPR036396 Cytochrome P450 superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00169 CholecalciferolDrugbanksmall molecule
DB00342 TerfenadineDrugbanksmall molecule
DB00637 AstemizoleDrugbanksmall molecule
DB01118 AmiodaroneDrugbanksmall molecule
DB04725 LicofeloneDrugbanksmall molecule
DB04855 DronedaroneDrugbanksmall molecule
DB06228 RivaroxabanDrugbanksmall molecule
DB06605 ApixabanDrugbanksmall molecule
DB08918 LevomilnacipranDrugbanksmall molecule
DB08931 RiociguatDrugbanksmall molecule
DB09030 VorapaxarDrugbanksmall molecule
DB09148 Florbetaben (18F)Drugbanksmall molecule
DB15305 RisdiplamSwissprotsmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CP2J2_HUMANELOC_HUMANBioGRID, IntAct21988832 details
CP2J2_HUMANZBT25_HUMANBioGRID, IntAct21988832 details