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Entity Details
Primary name
CLCN2_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P51788
EntryName
CLCN2_HUMAN
FullName
Chloride channel protein 2
TaxID
9606
Evidence
evidence at protein level
Length
898
SequenceStatus
complete
DateCreated
1996-10-01
DateModified
2021-06-02
Ontological Relatives
Genes
CLCN2
GO terms
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GO
Name
GO:0005247
voltage-gated chloride channel activity
GO:0005886
plasma membrane
GO:0005887
integral component of plasma membrane
GO:0006821
chloride transport
GO:0032347
regulation of aldosterone biosynthetic process
GO:0034220
ion transmembrane transport
GO:0034707
chloride channel complex
GO:0034765
regulation of ion transmembrane transport
GO:0060041
retina development in camera-type eye
GO:0060689
cell differentiation involved in salivary gland development
Subcellular Location
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Subcellular Location
Cell membrane
Domains
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Domain
Name
Category
Type
IPR000644
CBS domain
Domain
Domain
IPR001807
Chloride channel, voltage gated
Family
Family
IPR002244
Chloride channel ClC-2
Family
Family
IPR014743
Chloride channel, core
Family
Homologous superfamily
Diseases
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Drugs
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Drug
Name
Source
Type
DB01046
Lubiprostone
Drugbank
small molecule
DB05514
Cobiprostone
Drugbank
small molecule
Interactions
16 interactions
Interactor
Partner
Sources
Publications
Link
CLCN2_HUMAN
PP1A_HUMAN
BioGRID, IntAct
22321011
details
CLCN2_HUMAN
ATX1_HUMAN
BioGRID, IntAct
23275563
details
CLCN2_HUMAN
UBQL1_HUMAN
BioGRID, IntAct
26871637
details
CLCN2_HUMAN
FHL3_HUMAN
BioGRID
26871637
details
CLCN2_HUMAN
MLF1_HUMAN
IntAct
25036637
details
CLCN2_HUMAN
BAG2_HUMAN
IntAct
25036637
details
CLCN2_HUMAN
NUDC3_HUMAN
IntAct
25036637
details
CLCN2_HUMAN
PSMD2_HUMAN
IntAct
25036637
details
CLCN2_HUMAN
SGTA_HUMAN
IntAct
25036637
details
CLCN2_HUMAN
CHIP_HUMAN
IntAct
25036637
details
CLCN2_HUMAN
PTG3L_HUMAN
IntAct
25036637
details
CLCN2_HUMAN
AASD1_HUMAN
IntAct
25036637
details
CLCN2_HUMAN
CUL4A_HUMAN
BioGRID
32466489
details
CLCN2_HUMAN
CUL4B_HUMAN
BioGRID
32466489
details
CLCN2_HUMAN
DDB1_HUMAN
BioGRID
32466489
details
CLCN2_HUMAN
CRBN_HUMAN
BioGRID
32466489
details
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