Entity Details

Primary name MVD1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP53602
EntryNameMVD1_HUMAN
FullNameDiphosphomevalonate decarboxylase
TaxID9606
Evidenceevidence at protein level
Length400
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesMVD

GO terms

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GOName
GO:0004163 diphosphomevalonate decarboxylase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006489 dolichyl diphosphate biosynthetic process
GO:0006695 cholesterol biosynthetic process
GO:0008284 positive regulation of cell population proliferation
GO:0008299 isoprenoid biosynthetic process
GO:0019216 regulation of lipid metabolic process
GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway
GO:0030544 Hsp70 protein binding
GO:0042803 protein homodimerization activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylaseFamilyFamily
IPR006204 GHMP kinase N-terminal domainDomainDomain
IPR014721 Ribosomal protein S5 domain 2-type fold, subgroupFamilyHomologous superfamily
IPR020568 Ribosomal protein S5 domain 2-type foldFamilyHomologous superfamily
IPR029765 Diphosphomevalonate decarboxylaseFamilyFamily
IPR036554 GHMP kinase, C-terminal domain superfamilyFamilyHomologous superfamily
IPR041431 Mvd1, C-terminalDomainDomain

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
MVD1_HUMANGNB5_HUMANBioGRID, HPRD, IntAct16169070 details
MVD1_HUMANEF1G_HUMANBioGRID, HPRD, IntAct16169070 details
MVD1_HUMAN4EBP1_HUMANHPRD, IntAct16169070 details
MVD1_HUMANBTAF1_HUMANBioGRID, HPRD12646231 details
MVD1_HUMANGRP75_HUMANBioGRID, HPRD12646231 details
MVD1_HUMANMVD1_HUMANBioGRID, HPRD8626466 details