Entity Details

Primary name COPA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP53621
EntryNameCOPA_HUMAN
FullNameCoatomer subunit alpha
TaxID9606
Evidenceevidence at protein level
Length1224
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCOPA

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0005179 hormone activity
GO:0005198 structural molecule activity
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0006891 intra-Golgi vesicle-mediated transport
GO:0016020 membrane
GO:0030126 COPI vesicle coat
GO:0030133 transport vesicle
GO:0030157 pancreatic juice secretion
GO:0030426 growth cone
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic vesicle
Golgi apparatus membrane
Secreted

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR006692 Coatomer, WD associated regionDomainDomain
IPR010714 Coatomer, alpha subunit, C-terminalDomainDomain
IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamilyFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016391 Coatomer alpha subunitFamilyFamily
IPR019775 WD40 repeat, conserved siteSiteConserved site
IPR020472 G-protein beta WD-40 repeatRepeatRepeat
IPR024977 Anaphase-promoting complex subunit 4, WD40 domainDomainDomain
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

37 interactions

InteractorPartnerSourcesPublicationsLink
COPA_HUMANCOPE_HUMANBioGRID, HPRD, IntAct10921873 16169070 22939629 26344197 27684187 31712447 8858162 9482852 9751720 details
COPA_HUMANM2OM_HUMANBioGRID, HPRD, IntAct16169070 details
COPA_HUMANMTR1B_HUMANBioGRID, HPRD, IntAct17215244 26514267 details
COPA_HUMANMLH1_HUMANIntAct20706999 details
COPA_HUMANTMEDA_HUMANBioGRID, UniProt9472029 9751720 details
COPA_HUMANSAC1_HUMANBioGRID, HPRD, MINT14527956 details
COPA_HUMANDUX4_HUMANBioGRID, IntAct26816005 details
COPA_HUMANCOPG1_HUMANBioGRID, IntAct14729954 22939629 26344197 28514442 9751720 details
COPA_HUMANCOPB2_HUMANBioGRID, HPRD10921873 14729954 22863883 22939629 26344197 8537409 8940050 9482852 9751720 details
COPA_HUMANCOPB_HUMANBioGRID10921873 22939629 26344197 8940050 9482852 9751720 details
COPA_HUMANARFG1_HUMANBioGRID, HPRD12379802 details
COPA_HUMANCOPA_HUMANBioGRID9482852 9751720 details
COPA_HUMANCOPD_HUMANBioGRID, HPRD22863883 22939629 26344197 8940050 9751720 details
COPA_HUMANCOPZ1_HUMANBioGRID22863883 22939629 26344197 9751720 details
COPA_HUMANWBP1_HUMANBioGRID25894502 details
COPA_HUMANWBP2_HUMANBioGRID27578003 details
COPA_HUMANSCYL1_HUMANBioGRID30631079 details
COPA_HUMANPTEN_HUMANBioGRID31685992 details
COPA_HUMANCDC42_HUMANBioGRID31478661 details
COPA_HUMANSUMO2_HUMANBioGRID32786267 details
COPA_HUMANNEMO_HUMANIntAct14743216 details
COPA_HUMANPGFRB_HUMANBioGRID, HPRD9207175 details
COPA_HUMANBET1L_HUMANBioGRID12388752 details
COPA_HUMANSMN_HUMANBioGRID21300694 23727837 details
COPA_HUMANGEMI2_HUMANBioGRID21300694 details
COPA_HUMANDDX20_HUMANBioGRID21300694 details
COPA_HUMANCOPG2_HUMANBioGRID14729954 22939629 details
COPA_HUMANUBXN6_HUMANBioGRID22337587 details
COPA_HUMANLMAN1_HUMANBioGRID22337587 34079125 details
COPA_HUMANCD8A_HUMANBioGRID25894502 details
COPA_HUMANRN126_HUMANBioGRID26508657 details
COPA_HUMANF210A_HUMANBioGRID26472760 details
COPA_HUMANTM41B_HUMANBioGRID30352685 details
COPA_HUMANSOX2_HUMANBioGRID21280222 details
COPA_HUMANISG15_HUMANBioGRID33024031 details
COPA_HUMANSTX8_HUMANHPRD12388752 details
COPA_HUMANTMED2_HUMANHPRD8703076 details