Entity Details

Primary name LOXL3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP58215
EntryNameLOXL3_HUMAN
FullNameLysyl oxidase homolog 3
TaxID9606
Evidenceevidence at protein level
Length753
SequenceStatuscomplete
DateCreated2001-07-11
DateModified2021-06-02

Ontological Relatives

GenesLOXL3

GO terms

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GOName
GO:0001837 epithelial to mesenchymal transition
GO:0001968 fibronectin binding
GO:0004720 protein-lysine 6-oxidase activity
GO:0005044 scavenger receptor activity
GO:0005507 copper ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006954 inflammatory response
GO:0016020 membrane
GO:0018057 peptidyl-lysine oxidation
GO:0021510 spinal cord development
GO:0030199 collagen fibril organization
GO:0030324 lung development
GO:0045892 negative regulation of transcription, DNA-templated
GO:0060021 roof of mouth development
GO:0061053 somite development
GO:1905590 fibronectin fibril organization
GO:2000329 negative regulation of T-helper 17 cell lineage commitment
GO:2001046 positive regulation of integrin-mediated signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR001190 SRCR domainDomainDomain
IPR001695 Lysyl oxidaseFamilyFamily
IPR017448 SRCR-like domainDomainDomain
IPR019828 Lysyl oxidase, conserved siteSiteConserved site
IPR036772 SRCR-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
LOXL3_HUMANAPMAP_HUMANHPRD, IntAct16169070 details
LOXL3_HUMANFINC_HUMANmatrixdb26954549 details
LOXL3_HUMANP66B_HUMANmatrixdb25118846 details