Entity Details

Primary name RS15A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP62244
EntryNameRS15A_HUMAN
FullName40S ribosomal protein S15a
TaxID9606
Evidenceevidence at protein level
Length130
SequenceStatuscomplete
DateCreated2004-07-05
DateModified2021-06-02

Ontological Relatives

GenesRPS15A

GO terms

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GOName
GO:0003735 structural constituent of ribosome
GO:0070062 extracellular exosome
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0008284 positive regulation of cell population proliferation
GO:0009615 response to virus
GO:0019083 viral transcription
GO:0022627 cytosolic small ribosomal subunit
GO:0002181 cytoplasmic translation
GO:0005829 cytosol
GO:0006412 translation
GO:0022626 cytosolic ribosome
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006413 translational initiation
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0016020 membrane
GO:0045787 positive regulation of cell cycle

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000630 Ribosomal protein S8FamilyFamily
IPR035987 Ribosomal protein S8 superfamilyFamilyHomologous superfamily

Diseases

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Disease IDSourceNameDescription
618313 OMIMDiamond-Blackfan anemia 20 (DBA20)A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies. DBA20 inheritance is autosomal dominant. The disease may be caused by variants affecting the gene represented in this entry.

Interactions

34 interactions

InteractorPartnerSourcesPublicationsLink
RS15A_HUMANEWS_HUMANBioGRID, HPRD, IntAct16189514 details
RS15A_HUMANDX39B_HUMANHPRD, IntAct14667819 details
RS15A_HUMANCDC37_HUMANBioGRID, MINT21900206 details
RS15A_HUMANELF5_HUMANBioGRID, HPRD, IntAct16189514 details
RS15A_HUMANGELS_HUMANIntAct32814053 details
RS15A_HUMANDUX4_HUMANBioGRID, IntAct26816005 details
RS15A_HUMANWFS1_HUMANIntAct32814053 details
RS15A_HUMANFGFR3_HUMANIntAct32814053 details
RS15A_HUMANKIF1B_HUMANIntAct32814053 details
RS15A_HUMANHD_HUMANIntAct32814053 details
RS15A_HUMANVHL_HUMANBioGRID21942715 22234250 details
RS15A_HUMANCALM1_HUMANBioGRID15840729 details
RS15A_HUMANHSPB1_HUMANIntAct32814053 details
RS15A_HUMANGRN_HUMANIntAct32814053 details
RS15A_HUMANUBE3A_HUMANBioGRID26506232 details
RS15A_HUMANCALM3_HUMANBioGRID15840729 details
RS15A_HUMANCALM2_HUMANBioGRID15840729 details
RS15A_HUMANRNF11_HUMANIntAct32814053 details
RS15A_HUMANRHOU_HUMANBioGRID26598620 details
RS15A_HUMANPTEN_HUMANBioGRID26561776 31685992 details
RS15A_HUMANFBX7_HUMANBioGRID27503909 details
RS15A_HUMANERCC6_HUMANBioGRID31722399 details
RS15A_HUMANERPG3_HUMANBioGRID31722399 details
RS15A_HUMANRS15A_HUMANHPRD14667819 details
RS15A_HUMANNFKB2_HUMANIntAct14743216 details
RS15A_HUMANNEMO_HUMANIntAct14743216 details
RS15A_HUMANM3K14_HUMANIntAct14743216 details
RS15A_HUMANPARN_HUMANBioGRID29395067 details
RS15A_HUMANMGMT_HUMANBioGRID16226712 details
RS15A_HUMANITA4_HUMANBioGRID22623428 details
RS15A_HUMANAKTIP_HUMANBioGRID27512140 details
RS15A_HUMANZBTB1_HUMANBioGRID24657165 details
RS15A_HUMANNXF1_HUMANBioGRID29395067 details
RS15A_HUMANSOX2_HUMANBioGRID21280222 details