Entity Details

Primary name CACB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ02641
EntryNameCACB1_HUMAN
FullNameVoltage-dependent L-type calcium channel subunit beta-1
TaxID9606
Evidenceevidence at protein level
Length598
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesCACNB1

GO terms

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GOName
GO:0005245 voltage-gated calcium channel activity
GO:0005886 plasma membrane
GO:0005891 voltage-gated calcium channel complex
GO:0007268 chemical synaptic transmission
GO:0007528 neuromuscular junction development
GO:0008331 high voltage-gated calcium channel activity
GO:0042383 sarcolemma
GO:0045202 synapse
GO:0061337 cardiac conduction
GO:1901385 regulation of voltage-gated calcium channel activity
GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
GO:1904646 cellular response to amyloid-beta

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000584 Voltage-dependent calcium channel, L-type, beta subunitFamilyFamily
IPR001452 SH3 domainDomainDomain
IPR005443 Voltage-dependent calcium channel, L-type, beta-1 subunitFamilyFamily
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00153 ErgocalciferolDrugbanksmall molecule
DB00228 EnfluraneDrugbanksmall molecule
DB00243 RanolazineDrugbanksmall molecule
DB00252 PhenytoinDrugbanksmall molecule
DB00273 TopiramateDrugbanksmall molecule
DB00308 IbutilideDrugbanksmall molecule
DB00381 AmlodipineDrugbanksmall molecule
DB00393 NimodipineDrugbanksmall molecule
DB00421 SpironolactoneDrugbanksmall molecule
DB00653 Magnesium sulfateDrugbanksmall molecule
DB00825 LevomentholDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB01110 MiconazoleDrugbanksmall molecule
DB01118 AmiodaroneDrugbanksmall molecule
DB01388 MibefradilDrugbanksmall molecule
DB04855 DronedaroneDrugbanksmall molecule
DB09089 TrimebutineDrugbanksmall molecule
DB09230 AzelnidipineDrugbanksmall molecule
DB09231 BenidipineDrugbanksmall molecule
DB09232 CilnidipineDrugbanksmall molecule
DB09236 LacidipineDrugbanksmall molecule
DB09238 ManidipineDrugbanksmall molecule
DB11093 Calcium citrateDrugbanksmall molecule
DB11148 ButambenDrugbanksmall molecule
DB11348 Calcium PhosphateDrugbanksmall molecule
DB13746 BioallethrinDrugbanksmall molecule
DB13961 Fish oilDrugbankbiotech
DB14481 Calcium phosphate dihydrateDrugbanksmall molecule