Entity Details

Primary name CD47_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ08722
EntryNameCD47_HUMAN
FullNameLeukocyte surface antigen CD47
TaxID9606
Evidenceevidence at protein level
Length323
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesCD47

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007229 integrin-mediated signaling pathway
GO:0008284 positive regulation of cell population proliferation
GO:0009986 cell surface
GO:0016477 cell migration
GO:0022409 positive regulation of cell-cell adhesion
GO:0030198 extracellular matrix organization
GO:0032649 regulation of interferon-gamma production
GO:0032653 regulation of interleukin-10 production
GO:0032655 regulation of interleukin-12 production
GO:0032675 regulation of interleukin-6 production
GO:0032680 regulation of tumor necrosis factor production
GO:0035579 specific granule membrane
GO:0035696 monocyte extravasation
GO:0043312 neutrophil degranulation
GO:0045428 regulation of nitric oxide biosynthetic process
GO:0050729 positive regulation of inflammatory response
GO:0050766 positive regulation of phagocytosis
GO:0050870 positive regulation of T cell activation
GO:0050900 leukocyte migration
GO:0051496 positive regulation of stress fiber assembly
GO:0070053 thrombospondin receptor activity
GO:0070062 extracellular exosome
GO:0070821 tertiary granule membrane
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071349 cellular response to interleukin-12
GO:0086080 protein binding involved in heterotypic cell-cell adhesion
GO:0098632 cell-cell adhesion mediator activity
GO:1904669 ATP export
GO:1905450 negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR006704 Leukocyte surface antigen CD47FamilyFamily
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013147 CD47 transmembraneDomainDomain
IPR013270 CD47 immunoglobulin-likeDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR037805 Leukocyte surface antigen CD47, IgVDomainDomain

Diseases

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