Entity Details

Primary name ACSM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ08AH1
EntryNameACSM1_HUMAN
FullNameAcyl-coenzyme A synthetase ACSM1, mitochondrial
TaxID9606
Evidenceevidence at protein level
Length577
SequenceStatuscomplete
DateCreated2007-10-02
DateModified2021-06-02

Ontological Relatives

GenesACSM1

GO terms

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GOName
GO:0004321 fatty-acyl-CoA synthase activity
GO:0004467 long-chain fatty acid-CoA ligase activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0005759 mitochondrial matrix
GO:0006633 fatty acid biosynthetic process
GO:0006637 acyl-CoA metabolic process
GO:0006805 xenobiotic metabolic process
GO:0015645 fatty acid ligase activity
GO:0015980 energy derivation by oxidation of organic compounds
GO:0018858 benzoate-CoA ligase activity
GO:0018874 benzoate metabolic process
GO:0019395 fatty acid oxidation
GO:0019605 butyrate metabolic process
GO:0042632 cholesterol homeostasis
GO:0046872 metal ion binding
GO:0047760 butyrate-CoA ligase activity
GO:0070062 extracellular exosome
GO:0072562 blood microparticle
GO:0102391 decanoate-CoA ligase activity

Subcellular Location

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Subcellular Location
Mitochondrion
Mitochondrion matrix

Domains

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DomainNameCategoryType
IPR000873 AMP-dependent synthetase/ligaseDomainDomain
IPR020845 AMP-binding, conserved siteSiteConserved site
IPR025110 AMP-binding enzyme, C-terminal domainDomainDomain
IPR042099 ANL, N-terminal domainFamilyHomologous superfamily

Diseases

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Interactions

4 interactions

InteractorPartnerSourcesPublicationsLink
ACSM1_HUMANMTUS2_HUMANBioGRID, IntAct32296183 details
ACSM1_HUMANOSBL3_HUMANBioGRID, IntAct32296183 details
ACSM1_HUMANMAGA2_HUMANBioGRID, IntAct32296183 details
ACSM1_HUMANCKLF5_HUMANBioGRID, IntAct32296183 details