Entity Details

Primary name TNK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13470
EntryNameTNK1_HUMAN
FullNameNon-receptor tyrosine-protein kinase TNK1
TaxID9606
Evidenceevidence at protein level
Length666
SequenceStatuscomplete
DateCreated2005-02-15
DateModified2021-06-02

Ontological Relatives

GenesTNK1

GO terms

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GOName
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0006468 protein phosphorylation
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016020 membrane
GO:0030154 cell differentiation
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0045087 innate immune response
GO:0046777 protein autophosphorylation

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule