Entity Details

Primary name TIGIT
Entity type gene
Source Source Link

Details

PrimaryID201633
RefseqGene
SymbolTIGIT
NameT cell immunoreceptor with Ig and ITIM domains
Chromosome3
Location3q13.31
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-04-30
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTIGIT_HUMAN

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0032695 negative regulation of interleukin-12 production
GO:0032733 positive regulation of interleukin-10 production
GO:0042802 identical protein binding
GO:0050868 negative regulation of T cell activation

Diseases

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Interactions

8 interactions

InteractorPartnerSourcesPublicationsLink
TIGITNECTIN4BioGRID, IntAct21982860 details
TIGITNECTIN3BioGRID, IntAct21982860 details
TIGITPVRBioGRID, IntAct21982860 27978489 28515320 details
TIGITNECTIN2BioGRID, IntAct21982860 27978489 28515320 details
TIGITCD226IntAct25465800 details
TIGITMALBioGRID, IntAct32296183 details
TIGITPLLPBioGRID, IntAct32296183 details
TIGITTIGITIntAct27978489 details