Entity Details

Primary name PDE7A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13946
EntryNamePDE7A_HUMAN
FullNameHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
TaxID9606
Evidenceevidence at protein level
Length482
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesPDE7A

GO terms

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GOName
GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005829 cytosol
GO:0006198 cAMP catabolic process
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0019933 cAMP-mediated signaling
GO:0046872 metal ion binding

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002073 3'5'-cyclic nucleotide phosphodiesterase, catalytic domainDomainDomain
IPR003607 HD/PDEase domainDomainDomain
IPR023088 3'5'-cyclic nucleotide phosphodiesteraseFamilyFamily
IPR023174 3'5'-cyclic nucleotide phosphodiesterase, conserved siteSiteConserved site
IPR036971 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00201 CaffeineDrugbanksmall molecule
DB07954 3-isobutyl-1-methyl-7H-xanthineDrugbanksmall molecule
DB08602 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-oneDrugbanksmall molecule
DB09283 TrapidilDrugbanksmall molecule

Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink