Entity Details

Primary name FOXC2
Entity type gene
Source Source Link

Details

PrimaryID2303
RefseqGeneNG_012025
SymbolFOXC2
Nameforkhead box C2
Chromosome16
Location16q24.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1999-12-22
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsFOXC2_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001216 DNA-binding transcription activator activity
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001503 ossification
GO:0001569 branching involved in blood vessel morphogenesis
GO:0001656 metanephros development
GO:0001657 ureteric bud development
GO:0001756 somitogenesis
GO:0001946 lymphangiogenesis
GO:0001974 blood vessel remodeling
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007219 Notch signaling pathway
GO:0007498 mesoderm development
GO:0007507 heart development
GO:0008286 insulin receptor signaling pathway
GO:0009653 anatomical structure morphogenesis
GO:0009725 response to hormone
GO:0010595 positive regulation of endothelial cell migration
GO:0014032 neural crest cell development
GO:0016604 nuclear body
GO:0030154 cell differentiation
GO:0030199 collagen fibril organization
GO:0031490 chromatin DNA binding
GO:0033630 positive regulation of cell adhesion mediated by integrin
GO:0035050 embryonic heart tube development
GO:0035470 positive regulation of vascular wound healing
GO:0042802 identical protein binding
GO:0043010 camera-type eye development
GO:0043565 sequence-specific DNA binding
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046620 regulation of organ growth
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048343 paraxial mesodermal cell fate commitment
GO:0048703 embryonic viscerocranium morphogenesis
GO:0048844 artery morphogenesis
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0060038 cardiac muscle cell proliferation
GO:0072011 glomerular endothelium development
GO:0072112 glomerular visceral epithelial cell differentiation
GO:0072144 glomerular mesangial cell development
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:0097746 blood vessel diameter maintenance
GO:0120163 negative regulation of cold-induced thermogenesis
GO:1902257 negative regulation of apoptotic process involved in outflow tract morphogenesis
GO:1990837 sequence-specific double-stranded DNA binding
GO:1990841 promoter-specific chromatin binding

Diseases

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Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
FOXC2TRIM27BioGRID, IntAct25416956 details
FOXC2TAX1BP1BioGRID, IntAct25416956 details
FOXC2RBPMSBioGRID, IntAct25416956 details
FOXC2GOLGA2BioGRID, IntAct32296183 details
FOXC2KRTAP3-3BioGRID, IntAct32296183 details
FOXC2METTL27BioGRID, IntAct32296183 details
FOXC2CNOT7BioGRID25416956 details
FOXC2PIN1IntAct23878394 details
FOXC2PPP2R2ABioGRID, IntAct23878394 26496610 details
FOXC2KDM5BBioGRID19336002 details
FOXC2MYCIntAct21150319 details
FOXC2FOXC1BioGRID, MINT25609649 details
FOXC2EBF3BioGRID, MINT25609649 details
FOXC2HOXB13BioGRID, MINT25609649 details
FOXC2ZBTB34BioGRID, MINT25609649 details
FOXC2POU2F2BioGRID, MINT25609649 details
FOXC2SALL1BioGRID, MINT25609649 details
FOXC2ZNF536BioGRID, MINT25609649 details
FOXC2SATB2BioGRID, MINT25609649 details
FOXC2DLX5BioGRID, MINT25609649 details
FOXC2HOXD13BioGRID, MINT25609649 details
FOXC2C5orf24BioGRID, MINT25609649 details
FOXC2NR2F1BioGRID, MINT25609649 details
FOXC2HOXC13BioGRID, MINT25609649 details
FOXC2RIF1BioGRID, MINT25609649 details
FOXC2HOXB9BioGRID, MINT25609649 details
FOXC2SMARCA5BioGRID, MINT25609649 details
FOXC2CREB1BioGRID, MINT25609649 details
FOXC2UBP1BioGRID, MINT25609649 details
FOXC2PITX2BioGRID, MINT25609649 details
FOXC2AKAP8BioGRID, MINT25609649 details
FOXC2POU2F1BioGRID, MINT25609649 details
FOXC2NFIABioGRID, MINT25609649 details
FOXC2TFCP2BioGRID, MINT25609649 details
FOXC2HDAC2BioGRID, MINT25609649 details
FOXC2SATB1BioGRID, MINT25609649 details
FOXC2FOXC2BioGRID, MINT25609649 details
FOXC2PPP2R1ABioGRID, IntAct26496610 details
FOXC2PPP2R2DBioGRID, IntAct28514442 details
FOXC2LYARBioGRID, IntAct30021884 details
FOXC2DACH1BioGRID25609649 details