Entity Details

Primary name TFDP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14186
EntryNameTFDP1_HUMAN
FullNameTranscription factor Dp-1
TaxID9606
Evidenceevidence at protein level
Length410
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesTFDP1

GO terms

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GOName
GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000785 chromatin
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0008134 transcription factor binding
GO:0008544 epidermis development
GO:0019904 protein domain specific binding
GO:0043276 anoikis
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0070317 negative regulation of G0 to G1 transition
GO:0070345 negative regulation of fat cell proliferation
GO:0090575 RNA polymerase II transcription regulator complex
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:2000278 regulation of DNA biosynthetic process

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR003316 E2F/DP family, winged-helix DNA-binding domainDomainDomain
IPR014889 Transcription factor DP, C-terminalDomainDomain
IPR015648 Transcription factor DPFamilyFamily
IPR028313 Transcription factor DP1FamilyFamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily
IPR037241 E2F-DP heterodimerization regionFamilyHomologous superfamily
IPR038168 Transcription factor DP, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

27 interactions

InteractorPartnerSourcesPublicationsLink
TFDP1_HUMANE2F6_HUMANBioGRID, HPRD, IntAct, MINT15536069 16189514 20211142 24981860 25416956 26186194 26871637 27705803 28514442 32296183 9501179 9704927 details
TFDP1_HUMANSIAH1_HUMANBioGRID, IntAct21988832 details
TFDP1_HUMANCDK6_HUMANBioGRID, IntAct22094256 details
TFDP1_HUMANE2F1_HUMANBioGRID, HPRD, IntAct, MINT15133492 16360038 20211142 22327218 22629304 24981860 25368385 27705803 28542143 30867845 31130363 7739537 7892279 8405995 8816502 8816798 8832394 9199321 9501179 9704927 9780002 details
TFDP1_HUMANE2F4_HUMANBioGRID, HPRD, IntAct, MINT10540350 16360038 24981860 27705803 32296183 7892279 7958924 7958925 9199321 9343408 9501179 details
TFDP1_HUMANE2F2_HUMANBioGRID, HPRD, IntAct, MINT20211142 24981860 27705803 31130363 7739537 8755520 8832394 details
TFDP1_HUMANE2F5_HUMANBioGRID, HPRD, IntAct, MINT24981860 27705803 7760804 7892279 details
TFDP1_HUMANCDK2_HUMANBioGRID, IntAct25852190 9199321 details
TFDP1_HUMANTP53B_HUMANBioGRID8896460 details
TFDP1_HUMANP53_HUMANBioGRID, HPRD8557038 8816502 details
TFDP1_HUMANNPDC1_HUMANBioGRID, HPRD11042687 details
TFDP1_HUMANSOCS3_HUMANBioGRID18687693 details
TFDP1_HUMANCDK1_HUMANBioGRID9199321 details
TFDP1_HUMANCBP_HUMANBioGRID25368385 8932363 details
TFDP1_HUMANCDN2A_HUMANBioGRID16135794 details
TFDP1_HUMANARF_HUMANBioGRID16135794 details
TFDP1_HUMANOGT1_HUMANBioGRID32994395 details
TFDP1_HUMANDVL1_HUMANMINT22773187 details
TFDP1_HUMANNLK_HUMANMINT22773187 details
TFDP1_HUMANRB_HUMANBioGRID, IntAct, MINT16360038 17187060 24981860 27705803 7739537 details
TFDP1_HUMANE2F3_HUMANBioGRID, HPRD, IntAct, MINT24981860 27705803 31130363 7739537 8755520 8832394 details
TFDP1_HUMANCDK3_HUMANBioGRID8846921 details
TFDP1_HUMANRBL1_HUMANBioGRID7739537 details
TFDP1_HUMANCDC20_HUMANBioGRID25368385 details
TFDP1_HUMANCDC27_HUMANBioGRID25368385 details
TFDP1_HUMANAPC5_HUMANBioGRID25368385 details
TFDP1_HUMANSRTD2_HUMANHPRD11331592 details