Entity Details

Primary name GHR
Entity type gene
Source Source Link

Details

PrimaryID2690
RefseqGeneNG_011688
SymbolGHR
Namegrowth hormone receptor
Chromosome5
Location5p13.1-p12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1989-11-23
ModificationDate2021-06-22

Ontological Relatives

UniProt IDsGHR_HUMAN

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0004896 cytokine receptor activity
GO:0004903 growth hormone receptor activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006897 endocytosis
GO:0007259 receptor signaling pathway via JAK-STAT
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0017046 peptide hormone binding
GO:0019221 cytokine-mediated signaling pathway
GO:0019530 taurine metabolic process
GO:0019838 growth factor binding
GO:0019901 protein kinase binding
GO:0019955 cytokine binding
GO:0031623 receptor internalization
GO:0032355 response to estradiol
GO:0032870 cellular response to hormone stimulus
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0040014 regulation of multicellular organism growth
GO:0040018 positive regulation of multicellular organism growth
GO:0042445 hormone metabolic process
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0042976 activation of Janus kinase activity
GO:0043235 receptor complex
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046898 response to cycloheximide
GO:0048009 insulin-like growth factor receptor signaling pathway
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0060396 growth hormone receptor signaling pathway
GO:0060397 growth hormone receptor signaling pathway via JAK-STAT
GO:0070064 proline-rich region binding
GO:0070195 growth hormone receptor complex

Diseases

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Interactions

55 interactions

InteractorPartnerSourcesPublicationsLink
GHRNCOA6HPRD, IntAct10567404 10866662 details
GHRGH1BioGRID, IntAct17500058 24280222 31279174 7862673 8943276 9353194 details
GHRPTPN2BioGRID, HPRD, IntAct12907755 details
GHRPTPRBBioGRID, IntAct12907755 19167335 details
GHRPTPN1BioGRID, IntAct12907755 details
GHRPTPRHBioGRID, IntAct12907755 details
GHRPTPN9BioGRID, IntAct12907755 details
GHRPTPN3BioGRID, IntAct12907755 details
GHRDUSP7BioGRID, IntAct12907755 details
GHRCRKIntAct17474147 details
GHRGRB2BioGRID, HPRD, IntAct17474147 9632636 details
GHRNCK1BioGRID, IntAct17474147 25241761 details
GHRPIK3R1HPRD, IntAct17474147 9632636 details
GHRPLCG1BioGRID, IntAct17474147 9632636 details
GHRPTPRCIntAct19167335 details
GHRPTPRKIntAct19167335 details
GHRPTPRJIntAct19167335 details
GHRPTPN12IntAct19167335 details
GHRPTPN22IntAct19167335 details
GHRSTAT5BBioGRID, HPRD, IntAct25241761 8923468 details
GHRGHRBioGRID, DIP, HPRD16116438 24280222 8943276 details
GHRSGTABioGRID, HPRD12735788 details
GHRCISHBioGRID, HPRD10585430 12586763 25505247 details
GHRSOCS1BioGRID, HPRD10585430 details
GHRSOCS3BioGRID, HPRD10585430 details
GHRSOCS2BioGRID, HPRD10585430 12135564 16675548 21980433 25505247 28967904 details
GHRPTPN11BioGRID, HPRD10976913 9442080 9632636 details
GHRSHC1BioGRID, HPRD7535773 9632636 details
GHRSTAT3BioGRID, HPRD8923468 details
GHRBTRCBioGRID17500058 22034227 23607312 details
GHRPTPN13BioGRID12907755 details
GHRSTUB1BioGRID22433856 details
GHRSKP1BioGRID23607312 25505247 details
GHRPIK3R2BioGRID9632636 details
GHRSRPK2BioGRID26167880 details
GHRCUL5BioGRID25505247 details
GHRNEDD8BioGRID25505247 details
GHRRNF7BioGRID25505247 details
GHRELOCBioGRID25505247 details
GHRELOBBioGRID25505247 details
GHRCUL1BioGRID25505247 details
GHRFBXO31BioGRID25505247 details
GHRRBX1BioGRID25505247 details
GHRSTAT5ABioGRID, HPRD, IntAct25241761 8702683 details
GHRJAK2BioGRID, HPRD10502458 21347402 24280222 7540178 8063815 details
GHRGRB10BioGRID, HPRD9632636 details
GHRJAK1BioGRID, HPRD10502458 details
GHRTYK2BioGRID, HPRD10502458 details
GHRFBXW11BioGRID24280222 details
GHRIGF1RBioGRID15044591 details
GHRPTPN6HPRD9632636 details
GHRAP2A1HPRD10551776 details
GHRIRS1HPRD7782332 details
GHRGH2HPRD1955498 details
GHRTP53IntAct20227041 details