Entity Details

Primary name UBP10_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14694
EntryNameUBP10_HUMAN
FullNameUbiquitin carboxyl-terminal hydrolase 10
TaxID9606
Evidenceevidence at protein level
Length798
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesUSP10

GO terms

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GOName
GO:0002039 p53 binding
GO:0003723 RNA binding
GO:0004197 cysteine-type endopeptidase activity
GO:0004843 thiol-dependent deubiquitinase
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006914 autophagy
GO:0006974 cellular response to DNA damage stimulus
GO:0010506 regulation of autophagy
GO:0016579 protein deubiquitination
GO:0019985 translesion synthesis
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0032991 protein-containing complex
GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0044325 transmembrane transporter binding
GO:0045111 intermediate filament cytoskeleton
GO:0071347 cellular response to interleukin-1

Subcellular Location

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Subcellular Location
Cytoplasm
Early endosome
Nucleus

Domains

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DomainNameCategoryType
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolaseDomainDomain
IPR009818 Ataxin-2, C-terminalDomainDomain
IPR018200 Ubiquitin specific protease, conserved siteSiteConserved site
IPR028767 Ubiquitin carboxyl-terminal hydrolase 10FamilyFamily
IPR028889 Ubiquitin specific protease domainDomainDomain
IPR038765 Papain-like cysteine peptidase superfamilyFamilyHomologous superfamily

Diseases

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Interactions

90 interactions

InteractorPartnerSourcesPublicationsLink
UBP10_HUMANG3BP1_HUMANBioGRID, HPRD, IntAct, MINT11439350 19615732 21455491 23230274 23279204 24981860 24998844 26344197 26777405 27022092 28514442 29395067 31771591 31981475 32296183 32382008 33495715 details
UBP10_HUMANG3BP2_HUMANBioGRID, IntAct19615732 23279204 24981860 25416956 26186194 27022092 28514442 29378906 29395067 29892012 31515488 31981475 32296183 32382008 33495715 details
UBP10_HUMANRAD51_HUMANBioGRID, MINT25640309 details
UBP10_HUMANNEMO_HUMANBioGRID, MINT24270572 25861989 details
UBP10_HUMANRACK1_HUMANBioGRID, IntAct32296183 details
UBP10_HUMANGFAP_HUMANBioGRID, IntAct28514442 32814053 details
UBP10_HUMANJPH3_HUMANIntAct32814053 details
UBP10_HUMANSNX3_HUMANBioGRID, HPRD18632802 details
UBP10_HUMANP53_HUMANBioGRID20096447 24998844 30067985 30940456 32807901 details
UBP10_HUMANUBC_HUMANBioGRID19398555 23287719 29576527 details
UBP10_HUMANANDR_HUMANBioGRID16368182 details
UBP10_HUMANUBP10_HUMANBioGRID24998844 32382008 details
UBP10_HUMANSIR6_HUMANBioGRID24169447 29698567 details
UBP10_HUMANAAPK1_HUMANBioGRID26876938 30056112 details
UBP10_HUMANAAPK2_HUMANBioGRID26876938 details
UBP10_HUMANH2A2C_HUMANBioGRID21245042 details
UBP10_HUMANMSH2_HUMANBioGRID26975374 details
UBP10_HUMANYAP1_HUMANBioGRID29891922 31511647 32217697 details
UBP10_HUMANNOTC1_HUMANBioGRID30975888 details
UBP10_HUMANKLF4_HUMANBioGRID31748695 details
UBP10_HUMANSMAD4_HUMANBioGRID31721429 details
UBP10_HUMANWWTR1_HUMANBioGRID32217697 details
UBP10_HUMANHDAC6_HUMANBioGRID32382008 details
UBP10_HUMANMLP3B_HUMANBioGRID33577797 details
UBP10_HUMANANR28_HUMANBioGRID, IntAct24255178 28514442 29395067 details
UBP10_HUMANPP6R1_HUMANBioGRID, IntAct24255178 28514442 29395067 details
UBP10_HUMANYBOX1_HUMANBioGRID, HPIDb, IntAct23986595 25497084 26343856 details
UBP10_HUMANZC12A_HUMANBioGRID, MINT24270572 25861989 details
UBP10_HUMANANR52_HUMANBioGRID, IntAct28514442 29395067 details
UBP10_HUMANANR44_HUMANBioGRID, IntAct28514442 29395067 details
UBP10_HUMANPP6R2_HUMANBioGRID, IntAct28514442 29395067 details
UBP10_HUMANCFTR_HUMANBioGRID, IntAct19398555 20215869 21455491 22904170 details
UBP10_HUMANSCNNA_HUMANBioGRID, HPRD18632802 details
UBP10_HUMANIF4G1_HUMANBioGRID19615732 27003362 27022092 32382008 details
UBP10_HUMANMDM2_HUMANBioGRID20096447 details
UBP10_HUMANPABP1_HUMANBioGRID23230274 27022092 29395067 32382008 details
UBP10_HUMANPP6R3_HUMANBioGRID24255178 29395067 details
UBP10_HUMANPTEN_HUMANBioGRID24270891 28852924 30056112 details
UBP10_HUMANPCNA_HUMANBioGRID24768535 details
UBP10_HUMANTBX21_HUMANBioGRID24845384 details
UBP10_HUMANKMT2E_HUMANBioGRID26678539 details
UBP10_HUMANTBP_HUMANBioGRID26393420 details
UBP10_HUMANTANK_HUMANBioGRID25861989 details
UBP10_HUMANTRAF6_HUMANBioGRID25861989 details
UBP10_HUMANSNAI1_HUMANBioGRID28067227 31911859 details
UBP10_HUMANZEB1_HUMANBioGRID29119051 details
UBP10_HUMANRN168_HUMANBioGRID27558965 details
UBP10_HUMANRS6_HUMANBioGRID27022092 details
UBP10_HUMANIF2B3_HUMANBioGRID29212181 32382008 details
UBP10_HUMANHABP4_HUMANBioGRID28695742 29395067 details
UBP10_HUMANPAIRB_HUMANBioGRID28695742 29395067 34079125 details
UBP10_HUMANSNAI2_HUMANBioGRID29803676 details
UBP10_HUMANCTNB1_HUMANBioGRID30323974 details
UBP10_HUMANSQSTM_HUMANBioGRID30469013 31501480 details
UBP10_HUMANSYUA_HUMANBioGRID30469013 details
UBP10_HUMANMSI2H_HUMANBioGRID30604502 details
UBP10_HUMANTRAF4_HUMANBioGRID30940456 details
UBP10_HUMANCAPR1_HUMANBioGRID24981860 29395067 details
UBP10_HUMANFMR1_HUMANBioGRID29395067 details
UBP10_HUMANFXR2_HUMANBioGRID29395067 details
UBP10_HUMANMEX3B_HUMANBioGRID29395067 details
UBP10_HUMANNUFP2_HUMANBioGRID24981860 29395067 details
UBP10_HUMANTRI25_HUMANBioGRID29395067 details
UBP10_HUMANUBP2L_HUMANBioGRID29395067 details
UBP10_HUMANUNK_HUMANBioGRID29395067 details
UBP10_HUMANDDX1_HUMANBioGRID29395067 details
UBP10_HUMANIF2B2_HUMANBioGRID29395067 32382008 details
UBP10_HUMANKNTC1_HUMANBioGRID29395067 details
UBP10_HUMANPPP6_HUMANBioGRID29395067 details
UBP10_HUMANRS10_HUMANBioGRID29395067 details
UBP10_HUMANRS3A_HUMANBioGRID29395067 details
UBP10_HUMANSND1_HUMANBioGRID29395067 details
UBP10_HUMANTDRD3_HUMANBioGRID29395067 details
UBP10_HUMANTOP3B_HUMANBioGRID29395067 details
UBP10_HUMANRENT1_HUMANBioGRID29395067 32382008 details
UBP10_HUMANZ3H7A_HUMANBioGRID29395067 details
UBP10_HUMANYTHD1_HUMANBioGRID29395067 details
UBP10_HUMANYTHD2_HUMANBioGRID29395067 details
UBP10_HUMANYTHD3_HUMANBioGRID29395067 details
UBP10_HUMANZCCHV_HUMANBioGRID29395067 details
UBP10_HUMANHELZ_HUMANBioGRID29395067 details
UBP10_HUMANMKRN2_HUMANBioGRID29395067 details
UBP10_HUMANLARP4_HUMANBioGRID29395067 details
UBP10_HUMANFA98A_HUMANBioGRID29395067 details
UBP10_HUMANIF2B1_HUMANBioGRID29395067 32382008 details
UBP10_HUMANPUM1_HUMANBioGRID29395067 details
UBP10_HUMANTHUM3_HUMANBioGRID29395067 details
UBP10_HUMANENOA_HUMANBioGRID31511647 details
UBP10_HUMANCD36_HUMANBioGRID33197885 details
UBP10_HUMANSCNNG_HUMANHPRD18632802 details