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Entity Details
Primary name
HMGCL
Entity type
gene
Source
Source Link
Details
PrimaryID
3155
RefseqGene
NG_013061
Symbol
HMGCL
Name
3-hydroxy-3-methylglutaryl-CoA lyase
Chromosome
1
Location
1p36.11
TaxID
9606
Status
live
SourceGenome
genomic
SourceOrigin
natural
CreationDate
1998-08-17
ModificationDate
2021-06-11
Ontological Relatives
UniProt IDs
HMGCL_HUMAN
GO terms
Show/Hide Table
GO
Name
GO:0000062
fatty-acyl-CoA binding
GO:0000287
magnesium ion binding
GO:0001889
liver development
GO:0004419
hydroxymethylglutaryl-CoA lyase activity
GO:0005198
structural molecule activity
GO:0005739
mitochondrion
GO:0005759
mitochondrial matrix
GO:0005777
peroxisome
GO:0005782
peroxisomal matrix
GO:0005829
cytosol
GO:0006552
leucine catabolic process
GO:0006629
lipid metabolic process
GO:0006637
acyl-CoA metabolic process
GO:0007005
mitochondrion organization
GO:0007584
response to nutrient
GO:0008104
protein localization
GO:0030145
manganese ion binding
GO:0031406
carboxylic acid binding
GO:0032991
protein-containing complex
GO:0042594
response to starvation
GO:0046872
metal ion binding
GO:0046951
ketone body biosynthetic process
GO:0070542
response to fatty acid
Diseases
Show/Hide Table
Interactions
40 interactions
Interactor
Partner
Sources
Publications
Link
HMGCL
MS4A7
BioGRID, HPRD, IntAct
16169070
details
HMGCL
GTF2B
BioGRID, IntAct
21988832
details
HMGCL
ADAMTS10
BioGRID, MINT
21900206
details
HMGCL
ARL6IP1
BioGRID, MINT
21900206
details
HMGCL
DNAJA1
BioGRID, MINT
21900206
details
HMGCL
HES1
BioGRID, MINT
21900206
details
HMGCL
RNF126
BioGRID, MINT
21900206
details
HMGCL
PEX5
BioGRID
20178365
details
HMGCL
HSD17B10
BioGRID
22496890
details
HMGCL
SIRT4
IntAct
25525879
details
HMGCL
HSCB
BioGRID, IntAct
28380382
details
HMGCL
CAT
BioGRID, IntAct
29568061
details
HMGCL
PNPT1
BioGRID
26186194
details
HMGCL
FPGS
BioGRID
26186194
28514442
details
HMGCL
GLS
BioGRID
26186194
28514442
details
HMGCL
ALAS1
BioGRID
26186194
28514442
details
HMGCL
ACADVL
BioGRID
26186194
28514442
details
HMGCL
MGME1
BioGRID
26186194
28514442
details
HMGCL
FBXO21
BioGRID
26186194
details
HMGCL
MCCC2
BioGRID
26344197
details
HMGCL
PIR
BioGRID
26344197
details
HMGCL
LSM12
BioGRID
26344197
details
HMGCL
TOMM40
BioGRID
26344197
details
HMGCL
HMGCLL1
BioGRID
28514442
details
HMGCL
NTAQ1
BioGRID
28514442
details
HMGCL
COX17
BioGRID
31536960
details
HMGCL
RAB7A
BioGRID
31536960
details
HMGCL
FABP3
BioGRID
31536960
details
HMGCL
LYPLAL1
BioGRID
31536960
details
HMGCL
ALDH4A1
BioGRID
31536960
details
HMGCL
RAB1A
BioGRID
31536960
details
HMGCL
CYB5R3
BioGRID
31536960
details
HMGCL
TXNDC12
BioGRID
31536960
details
HMGCL
RAB11A
BioGRID
31536960
details
HMGCL
MSRB2
BioGRID
31536960
details
HMGCL
INHBA
BioGRID
31536960
details
HMGCL
BIRC3
BioGRID
30948266
details
HMGCL
PLEKHA4
BioGRID
31091453
details
HMGCL
INS
BioGRID
32457219
details
HMGCL
CUL4A
BioGRID
32235678
details
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