Entity Details

Primary name IFNGR1
Entity type gene
Source Source Link

Details

PrimaryID3459
RefseqGeneNG_007394
SymbolIFNGR1
Nameinterferon gamma receptor 1
Chromosome6
Location6q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1995-08-15
ModificationDate2021-06-19

Ontological Relatives

UniProt IDsINGR1_HUMAN

GO terms

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GOName
GO:0001774 microglial cell activation
GO:0004896 cytokine receptor activity
GO:0004906 interferon-gamma receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007165 signal transduction
GO:0009615 response to virus
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0019221 cytokine-mediated signaling pathway
GO:0019955 cytokine binding
GO:0032760 positive regulation of tumor necrosis factor production
GO:0048143 astrocyte activation
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060334 regulation of interferon-gamma-mediated signaling pathway
GO:1900222 negative regulation of amyloid-beta clearance
GO:1902004 positive regulation of amyloid-beta formation

Diseases

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Interactions

53 interactions

InteractorPartnerSourcesPublicationsLink
IFNGR1IFNGBioGRID, DIP, HPRD, IntAct10986460 11250200 12165521 28514442 7617032 7673114 details
IFNGR1STAT1BioGRID, HPRD, MINT10848598 15494521 15780933 21689637 7514165 8156998 8662591 details
IFNGR1TMEM237BioGRID, IntAct32296183 details
IFNGR1TMEM100BioGRID, IntAct32296183 details
IFNGR1SLC9A6BioGRID, IntAct28514442 32296183 details
IFNGR1RUSF1BioGRID, IntAct28514442 32296183 details
IFNGR1STIM1BioGRID, IntAct32296183 details
IFNGR1AQP6BioGRID, IntAct32296183 details
IFNGR1NINJ2BioGRID, IntAct32296183 details
IFNGR1JAK1BioGRID, HPRD, IntAct12133952 21689637 28514442 details
IFNGR1NFKB1IntAct20195357 details
IFNGR1MAD2L2BioGRID, IntAct28514442 30022168 details
IFNGR1JAK2BioGRID, HPRD11438544 21689637 7499845 7673114 details
IFNGR1H3C14BioGRID21689637 details
IFNGR1DTX3LBioGRID24886089 details
IFNGR1SOCS1BioGRID, HPRD15522878 29991678 details
IFNGR1PARP9BioGRID23487038 details
IFNGR1CANXHPRD8136357 details
IFNGR1IFNGR2HPRD7673114 details
IFNGR1IFNGR1HPRD10986460 details
IFNGR1RAC1HPRD15494521 details
IFNGR1PTPN11HPRD10022928 details
IFNGR1TMEM30BBioGRID, IntAct28514442 details
IFNGR1ADGRG5BioGRID, IntAct28514442 details
IFNGR1RAET1EBioGRID, IntAct28514442 details
IFNGR1TNFRSF10BBioGRID, IntAct26186194 28514442 details
IFNGR1NOTCH3BioGRID, IntAct28514442 details
IFNGR1CD320BioGRID, IntAct28514442 details
IFNGR1NDFIP1BioGRID, IntAct28514442 details
IFNGR1LRP10BioGRID, IntAct28514442 details
IFNGR1RHOUBioGRID, IntAct28514442 details
IFNGR1BMPR1ABioGRID, IntAct28514442 details
IFNGR1SRCBioGRID, IntAct28514442 details
IFNGR1FGFR1BioGRID, IntAct28514442 details
IFNGR1TSPAN3BioGRID26186194 details
IFNGR1IL20RBBioGRID26186194 details
IFNGR1KRASBioGRID30194290 30639242 details
IFNGR1HRASBioGRID30194290 details
IFNGR1NRASBioGRID30194290 details
IFNGR1SLX4IPBioGRID31495888 details
IFNGR1B3GAT1BioGRID34079125 details
IFNGR1CAV1BioGRID34079125 details
IFNGR1EBAG9BioGRID34079125 details
IFNGR1ELOVL5BioGRID34079125 details
IFNGR1GJD3BioGRID34079125 details
IFNGR1OCLNBioGRID34079125 details
IFNGR1RAB11ABioGRID34079125 details
IFNGR1RHOBBioGRID34079125 details
IFNGR1STX4BioGRID34079125 details
IFNGR1STX7BioGRID34079125 details
IFNGR1SHMT2BioGRID22658674 details
IFNGR1MOV10BioGRID22658674 details
IFNGR1NXF1BioGRID22658674 details