Entity Details

Primary name IDO1
Entity type gene
Source Source Link

Details

PrimaryID3620
RefseqGeneNG_028155
SymbolIDO1
Nameindoleamine 2,3-dioxygenase 1
Chromosome8
Location8p11.21
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-19
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsI23O1_HUMAN

GO terms

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GOName
GO:0002376 immune system process
GO:0002666 positive regulation of T cell tolerance induction
GO:0002678 positive regulation of chronic inflammatory response
GO:0002830 positive regulation of type 2 immune response
GO:0004833 tryptophan 2,3-dioxygenase activity
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006569 tryptophan catabolic process
GO:0006954 inflammatory response
GO:0007565 female pregnancy
GO:0009055 electron transfer activity
GO:0019441 tryptophan catabolic process to kynurenine
GO:0020037 heme binding
GO:0030485 smooth muscle contractile fiber
GO:0032421 stereocilium bundle
GO:0032496 response to lipopolysaccharide
GO:0032693 negative regulation of interleukin-10 production
GO:0032735 positive regulation of interleukin-12 production
GO:0033555 multicellular organismal response to stress
GO:0033754 indoleamine 2,3-dioxygenase activity
GO:0034276 kynurenic acid biosynthetic process
GO:0034354 'de novo' NAD biosynthetic process from tryptophan
GO:0036269 swimming behavior
GO:0042130 negative regulation of T cell proliferation
GO:0046872 metal ion binding
GO:0070233 negative regulation of T cell apoptotic process
GO:0070234 positive regulation of T cell apoptotic process

Diseases

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Interactions

5 interactions

InteractorPartnerSourcesPublicationsLink
IDO1PPP1R16ABioGRID, HPRD, IntAct16169070 details
IDO1DDX24HPRD, IntAct16169070 details
IDO1TERF2IPbhf-ucl, BioGRID21044950 details
IDO1APPBioGRID21832049 details
IDO1FBXL17BioGRID31560077 details