Entity Details

Primary name ACHA6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15825
EntryNameACHA6_HUMAN
FullNameNeuronal acetylcholine receptor subunit alpha-6
TaxID9606
Evidenceevidence at protein level
Length494
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCHRNA6

GO terms

Show/Hide Table
GOName
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005892 acetylcholine-gated channel complex
GO:0007165 signal transduction
GO:0007268 chemical synaptic transmission
GO:0015464 acetylcholine receptor activity
GO:0022848 acetylcholine-gated cation-selective channel activity
GO:0030594 neurotransmitter receptor activity
GO:0034220 ion transmembrane transport
GO:0042391 regulation of membrane potential
GO:0043005 neuron projection
GO:0045202 synapse
GO:0045211 postsynaptic membrane
GO:0050877 nervous system process

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR002394 Nicotinic acetylcholine receptorFamilyFamily
IPR006029 Neurotransmitter-gated ion-channel transmembrane domainDomainDomain
IPR006201 Neurotransmitter-gated ion-channelFamilyFamily
IPR006202 Neurotransmitter-gated ion-channel ligand-binding domainDomainDomain
IPR018000 Neurotransmitter-gated ion-channel, conserved siteSiteConserved site
IPR036719 Neurotransmitter-gated ion-channel transmembrane domain superfamilyFamilyHomologous superfamily
IPR036734 Neurotransmitter-gated ion-channel ligand-binding domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00184 NicotineDrugbanksmall molecule
DB00237 ButabarbitalDrugbanksmall molecule
DB00898 EthanolDrugbanksmall molecule
DB01273 VareniclineDrugbanksmall molecule
DB09028 CytisineDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ACHA6_HUMANCANB1_HUMANBioGRID, IntAct27107012 details