Entity Details

Primary name OAS2
Entity type gene
Source Source Link

Details

PrimaryID4939
RefseqGeneNG_029692
SymbolOAS2
Name2'-5'-oligoadenylate synthetase 2
Chromosome12
Location12q24.13
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-08
ModificationDate2021-06-13

Ontological Relatives

UniProt IDsOAS2_HUMAN

GO terms

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GOName
GO:0001730 2'-5'-oligoadenylate synthetase activity
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006139 nucleobase-containing compound metabolic process
GO:0006401 RNA catabolic process
GO:0009615 response to virus
GO:0016020 membrane
GO:0032728 positive regulation of interferon-beta production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0042742 defense response to bacterium
GO:0043231 intracellular membrane-bounded organelle
GO:0045071 negative regulation of viral genome replication
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0051607 defense response to virus
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon signaling pathway
GO:0060700 regulation of ribonuclease activity
GO:0070106 interleukin-27-mediated signaling pathway
GO:1903487 regulation of lactation

Diseases

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Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
OAS2CLK3BioGRID, IntAct25416956 31515488 32296183 details
OAS2FBXO17BioGRID, IntAct32296183 details
OAS2APPBioGRID21832049 details
OAS2SASH1BioGRID30480076 details
OAS2CGASBioGRID30471916 details
OAS2GIMAP8BioGRID, IntAct28514442 details
OAS2PRKG1BioGRID, IntAct28514442 details
OAS2ACACABioGRID, IntAct28514442 details
OAS2TP53BioGRID32807901 details