Entity Details

Primary name KAT1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16773
EntryNameKAT1_HUMAN
FullNameKynurenine--oxoglutarate transaminase 1
TaxID9606
Evidenceevidence at protein level
Length422
SequenceStatuscomplete
DateCreated2004-04-13
DateModified2021-06-02

Ontological Relatives

GenesKYAT1

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0006558 L-phenylalanine metabolic process
GO:0006569 tryptophan catabolic process
GO:0006575 cellular modified amino acid metabolic process
GO:0009058 biosynthetic process
GO:0009064 glutamine family amino acid metabolic process
GO:0016212 kynurenine-oxoglutarate transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0042803 protein homodimerization activity
GO:0047316 glutamine-phenylpyruvate transaminase activity
GO:0047804 cysteine-S-conjugate beta-lyase activity
GO:0070189 kynurenine metabolic process
GO:0097053 L-kynurenine catabolic process

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004839 Aminotransferase, class I/classIIDomainDomain
IPR015421 Pyridoxal phosphate-dependent transferase, major domainFamilyHomologous superfamily
IPR015422 Pyridoxal phosphate-dependent transferase, small domainFamilyHomologous superfamily
IPR015424 Pyridoxal phosphate-dependent transferaseFamilyHomologous superfamily
IPR034614 Kynurenine--oxoglutarate transaminase 1FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00114 Pyridoxal phosphateDrugbanksmall molecule
DB00130 L-GlutamineDrugbanksmall molecule
DB02142 Pyridoxamine-5'-PhosphateDrugbanksmall molecule
DB02556 D-PhenylalanineDrugbanksmall molecule
DB04083 N(6)-(pyridoxal phosphate)-L-lysineDrugbanksmall molecule
DB07950 Indoleacetic acidDrugbanksmall molecule