Entity Details

Primary name PPP2CB
Entity type gene
Source Source Link

Details

PrimaryID5516
RefseqGene
SymbolPPP2CB
Nameprotein phosphatase 2 catalytic subunit beta
Chromosome8
Location8p12
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-05-03
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsPP2AB_HUMAN

GO terms

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GOName
GO:0000159 protein phosphatase type 2A complex
GO:0000775 chromosome, centromeric region
GO:0000922 spindle pole
GO:0004722 protein serine/threonine phosphatase activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0006470 protein dephosphorylation
GO:0008022 protein C-terminus binding
GO:0008637 apoptotic mitochondrial changes
GO:0010288 response to lead ion
GO:0010468 regulation of gene expression
GO:0034976 response to endoplasmic reticulum stress
GO:0035970 peptidyl-threonine dephosphorylation
GO:0042542 response to hydrogen peroxide
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0046580 negative regulation of Ras protein signal transduction
GO:0046677 response to antibiotic
GO:0046872 metal ion binding
GO:0048156 tau protein binding
GO:0070262 peptidyl-serine dephosphorylation
GO:0106306 protein serine phosphatase activity
GO:0106307 protein threonine phosphatase activity
GO:1904528 positive regulation of microtubule binding

Diseases

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Interactions

202 interactions

InteractorPartnerSourcesPublicationsLink
PPP2CBPPP2R1ABioGRID, IntAct, MINT12370081 15936019 18782753 19156129 23443559 24981860 26186194 26344197 26496610 27173435 27880917 28330616 28514442 unassigned1312 details
PPP2CBPPP2R1BBioGRID, IntAct12370081 19156129 26186194 26344197 26496610 28514442 details
PPP2CBIGBP1BioGRID, IntAct, UniProt18782753 19156129 26344197 26496610 27880917 9647778 details
PPP2CBTIPRLBioGRID, IntAct16085932 26344197 27880917 details
PPP2CBFHL1MINT20969868 details
PPP2CBGSTA1BioGRID, IntAct21988832 details
PPP2CBHK3BioGRID, IntAct21988832 details
PPP2CBMAKBioGRID, IntAct21988832 details
PPP2CBRAF1BioGRID, IntAct21988832 details
PPP2CBTAB2BioGRID, IntAct21988832 details
PPP2CBTRMT61BBioGRID, IntAct21988832 details
PPP2CBTAB1BioGRID, IntAct21988832 details
PPP2CBACP5BioGRID, MINT21900206 details
PPP2CBC22orf39BioGRID, MINT21900206 details
PPP2CBDOCK7BioGRID, MINT21900206 details
PPP2CBPLXNA3BioGRID, MINT21900206 details
PPP2CBRPLP1BioGRID, MINT21900206 details
PPP2CBDYNLT2BBioGRID, MINT21900206 details
PPP2CBZFP28BioGRID, MINT21900206 details
PPP2CBZNF775BioGRID, MINT21900206 details
PPP2CBAXIN2MINT10698523 details
PPP2CBAURKABioGRID, MINT24412244 details
PPP2CBBUB1BioGRID, MINT24412244 details
PPP2CBEGFRBioGRID, MINT24412244 details
PPP2CBKRASBioGRID, MINT24412244 details
PPP2CBMLH1BioGRID, MINT24412244 details
PPP2CBMLH3BioGRID, MINT24412244 details
PPP2CBNRASBioGRID, MINT24412244 details
PPP2CBPDGFRLBioGRID, MINT24412244 details
PPP2CBPMS2BioGRID, MINT24412244 details
PPP2CBPTPRJBioGRID, MINT24412244 details
PPP2CBSMAD4BioGRID, MINT24412244 details
PPP2CBSRCBioGRID, MINT24412244 details
PPP2CBSTK11BioGRID, MINT24412244 details
PPP2CBTGFBR2BioGRID, MINT24412244 details
PPP2CBFMR1IntAct32814053 details
PPP2CBTLX1BioGRID9009195 details
PPP2CBRELABioGRID11591705 details
PPP2CBBHLHE41BioGRID23555304 details
PPP2CBMAPTBioGRID16262633 7616230 details
PPP2CBMCCIntAct17353931 details
PPP2CBEIF6IntAct17353931 details
PPP2CBTFE3IntAct17353931 details
PPP2CBCCNA1IntAct17353931 details
PPP2CBHLA-BIntAct17353931 details
PPP2CBTRAF6IntAct17353931 details
PPP2CBGH1IntAct17353931 details
PPP2CBIKBKEIntAct17353931 details
PPP2CBSTRIP1BioGRID, DIP, IntAct18782753 19156129 25531779 26186194 26496610 28514442 details
PPP2CBSTRN4BioGRID, IntAct18782753 19156129 26186194 26496610 28514442 details
PPP2CBCTTNBP2NLBioGRID, IntAct18782753 19156129 26186194 26496610 28514442 details
PPP2CBINTS6BioGRID, IntAct20133760 26496610 details
PPP2CBSTRIP2BioGRID, DIP, IntAct25531779 26186194 26496610 28514442 details
PPP2CBPRR14BioGRID, IntAct19156129 26186194 28514442 details
PPP2CBDISC1IntAct31413325 details
PPP2CBARL2BioGRID12912990 details
PPP2CBINTS1BioGRID20133760 26496610 details
PPP2CBINTS3BioGRID20133760 details
PPP2CBINTS5BioGRID20133760 details
PPP2CBTERF1BioGRID20811636 details
PPP2CBACTBL2BioGRID19156129 details
PPP2CBMYLPFBioGRID19156129 details
PPP2CBMYH10BioGRID19156129 details
PPP2CBADARB1BioGRID19156129 details
PPP2CBHDAC5BioGRID21081666 details
PPP2CBCDC20BioGRID26811472 details
PPP2CBNOSIPBioGRID25546391 details
PPP2CBMARK4BioGRID, IntAct14676191 details
PPP2CBSTK24BioGRID, IntAct17353931 23455922 26496610 details
PPP2CBPPP4CBioGRID, IntAct17353931 26496610 27880917 details
PPP2CBSGO1BioGRID, IntAct19156129 26186194 28514442 details
PPP2CBPFDN2BioGRID, IntAct19156129 details
PPP2CBSLMAPBioGRID, IntAct19156129 26186194 26496610 28514442 details
PPP2CBPPP2R5DBioGRID, IntAct18782753 19156129 26186194 26344197 26496610 27880917 28514442 details
PPP2CBPPP2R5EBioGRID, IntAct19156129 26186194 26344197 26496610 27880917 28514442 details
PPP2CBPPP2R2ABioGRID, IntAct18782753 19156129 26186194 26344197 26496610 27880917 28330616 28514442 details
PPP2CBANKLE2BioGRID, IntAct19156129 26186194 26496610 27880917 28514442 details
PPP2CBVBP1BioGRID, IntAct19156129 details
PPP2CBPFDN6BioGRID, IntAct19156129 details
PPP2CBPRR14LBioGRID, IntAct19156129 26186194 28514442 details
PPP2CBPFDN5BioGRID, IntAct19156129 details
PPP2CBPPP2R5CBioGRID, IntAct19156129 26186194 27880917 28514442 details
PPP2CBSIKE1BioGRID, IntAct19156129 26186194 26496610 28514442 details
PPP2CBCCT5BioGRID, IntAct18782753 19156129 26496610 details
PPP2CBPPME1BioGRID, IntAct19156129 26186194 26499835 27880917 28514442 details
PPP2CBTCP1BioGRID, IntAct18782753 19156129 26496610 details
PPP2CBCCT2BioGRID, IntAct18782753 19156129 26496610 details
PPP2CBMOB4BioGRID, IntAct18782753 19156129 26186194 26496610 28514442 details
PPP2CBCCT3BioGRID, IntAct18782753 19156129 26496610 details
PPP2CBCCT8BioGRID, IntAct18782753 19156129 26496610 details
PPP2CBSTRNBioGRID, IntAct18782753 19156129 26186194 26496610 28514442 details
PPP2CBCCT4BioGRID, IntAct18782753 19156129 26496610 details
PPP2CBCCT7BioGRID, IntAct18782753 19156129 26496610 details
PPP2CBPPFIA1BioGRID, IntAct19156129 26186194 26496610 27880917 28514442 details
PPP2CBSTRN3BioGRID, IntAct18782753 19156129 26186194 26496610 28514442 details
PPP2CBCCT6ABioGRID, IntAct18782753 19156129 26496610 details
PPP2CBPPP2R2BBioGRID, IntAct19156129 26344197 28330616 details
PPP2CBPPP2R2DBioGRID, IntAct19156129 26186194 26344197 27880917 28330616 28514442 details
PPP2CBCEP43BioGRID, IntAct18782753 26186194 26496610 28514442 details
PPP2CBCTTNBP2BioGRID, IntAct18782753 26186194 28514442 details
PPP2CBCBX5BioGRID, UniProt20562864 details
PPP2CBFOXO3BioGRID, MINT20110348 26280018 details
PPP2CBLRFN4MINT22677168 details
PPP2CBSTK25BioGRID, IntAct23455922 details
PPP2CBSTK26BioGRID, IntAct23455922 details
PPP2CBCDK16BioGRID, IntAct23602568 details
PPP2CBCDK17BioGRID, IntAct23602568 details
PPP2CBCDK18BioGRID, IntAct23602568 details
PPP2CBCILK1IntAct23602568 details
PPP2CBERBB2IntAct24189400 details
PPP2CBL3MBTL3BioGRID, IntAct27705803 details
PPP2CBKSR1IntAct24525234 details
PPP2CBARHGEF2BioGRID, IntAct24525234 27880917 details
PPP2CBINTS4BioGRID, IntAct26496610 details
PPP2CBFECHBioGRID, IntAct26186194 26496610 27880917 28514442 details
PPP2CBTMEM41BBioGRID, IntAct26496610 details
PPP2CBPLEKHA5BioGRID, IntAct26496610 details
PPP2CBCCDC6BioGRID, IntAct26186194 26496610 27880917 28514442 details
PPP2CBINTS11BioGRID, IntAct26496610 details
PPP2CBMARK3BioGRID, IntAct26496610 details
PPP2CBINTS12BioGRID, IntAct26496610 details
PPP2CBCEP72BioGRID, IntAct26496610 details
PPP2CBPPP2R3BBioGRID, IntAct26186194 26496610 27880917 28514442 details
PPP2CBCEP131BioGRID, IntAct26496610 details
PPP2CBFGFR1OP2BioGRID, IntAct26186194 26496610 28514442 details
PPP2CBPPP4R1BioGRID, IntAct26186194 26496610 27880917 28514442 details
PPP2CBDECR2BioGRID, IntAct26496610 details
PPP2CBPDCD10BioGRID, IntAct26496610 details
PPP2CBINTS9BioGRID, IntAct26496610 details
PPP2CBCEP350BioGRID, IntAct26186194 26496610 28514442 details
PPP2CBCCDC61BioGRID, IntAct26496610 details
PPP2CBPPP4R3BBioGRID, IntAct26496610 details
PPP2CBPPFIA3BioGRID, IntAct26496610 27880917 details
PPP2CBMAP7BioGRID, IntAct26496610 details
PPP2CBSETBioGRID, IntAct26496610 details
PPP2CBPKN3BioGRID, IntAct26496610 details
PPP2CBBCAR1bhf-ucl28007913 details
PPP2CBPPP2R2CBioGRID, IntAct28330616 details
PPP2CBPLEKHA7IntAct28877994 details
PPP2CBFOXD4BioGRID, IntAct28514442 details
PPP2CBTBCCD1BioGRID, IntAct26186194 28514442 details
PPP2CBPPP2R3CBioGRID, IntAct26186194 28514442 details
PPP2CBZNF444BioGRID, IntAct26186194 28514442 details
PPP2CBPPP2R5ABioGRID, IntAct26186194 27880917 28514442 details
PPP2CBANGMINT28777577 details
PPP2CBNEK4BioGRID, MINT25798074 details
PPP2CBIFT81BioGRID, IntAct30021884 details
PPP2CBMAP2K3BioGRID, IntAct31980649 details
PPP2CBHRBioGRID, MINT24981860 details
PPP2CBNDNBioGRID, MINT32529326 details
PPP2CBNOTCH1BioGRID23022380 details
PPP2CBVCPBioGRID23383273 details
PPP2CBITGA4BioGRID22623428 details
PPP2CBAARSD1BioGRID22863883 details
PPP2CBATG7BioGRID22863883 details
PPP2CBNIF3L1BioGRID22863883 details
PPP2CBNSUN2BioGRID22863883 details
PPP2CBELAC2BioGRID22863883 details
PPP2CBWDR12BioGRID22863883 details
PPP2CBTTC1BioGRID22863883 details
PPP2CBASB5BioGRID24337577 details
PPP2CBSNAI2BioGRID23851495 details
PPP2CBNDUFAF1BioGRID26186194 details
PPP2CBFOXC1BioGRID26186194 27880917 details
PPP2CBSERTAD4BioGRID26186194 details
PPP2CBHMGCS1BioGRID26344197 details
PPP2CBPPP2CABioGRID26344197 27880917 details
PPP2CBIFI16BioGRID25693804 details
PPP2CBMAP4K4BioGRID26496610 details
PPP2CBINTS2BioGRID26496610 details
PPP2CBCRY1BioGRID25756610 details
PPP2CBCRY2BioGRID25756610 details
PPP2CBESR1BioGRID26389696 details
PPP2CBESRRBBioGRID24189400 details
PPP2CBCAMSAP3BioGRID27880917 details
PPP2CBENSABioGRID27880917 details
PPP2CBPABIR1BioGRID27880917 details
PPP2CBPABIR2BioGRID27880917 details
PPP2CBFBXL16BioGRID27880917 details
PPP2CBIKBioGRID27880917 details
PPP2CBPTPABioGRID27880917 details
PPP2CBTBC1D4BioGRID27880917 details
PPP2CBTTC33BioGRID27880917 details
PPP2CBWDR61BioGRID27880917 details
PPP2CBURI1BioGRID27780869 details
PPP2CBBRAFBioGRID27034005 details
PPP2CBMAXBioGRID29028833 details
PPP2CBEP400BioGRID29028833 details
PPP2CBCFTRBioGRID26618866 details
PPP2CBRIOK1BioGRID21081503 details
PPP2CBESR2BioGRID29509190 details
PPP2CBLARP7BioGRID29845934 details
PPP2CBSNAI1BioGRID29331416 details
PPP2CBCUL4ABioGRID30945288 32235678 details
PPP2CBABCC6BioGRID29704455 details
PPP2CBTRIM28BioGRID29955894 details
PPP2CBPLEKHA4BioGRID31091453 details
PPP2CBNMRAL1BioGRID31796584 details
PPP2CBCICBioGRID29844126 details
PPP2CBZFP36BioGRID21784977 details
PPP2CBTRIM25BioGRID29117863 details
PPP2CBHNRNPH1BioGRID26760575 details