Entity Details

Primary name CLCA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionA8K7I4
EntryNameCLCA1_HUMAN
FullNameCalcium-activated chloride channel regulator 1
TaxID9606
Evidenceevidence at protein level
Length914
SequenceStatuscomplete
DateCreated2008-05-20
DateModified2021-06-02

Ontological Relatives

GenesCLCA1

GO terms

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GOName
GO:0005229 intracellular calcium activated chloride channel activity
GO:0005254 chloride channel activity
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005902 microvillus
GO:0006816 calcium ion transport
GO:0006821 chloride transport
GO:0008237 metallopeptidase activity
GO:0034220 ion transmembrane transport
GO:0042589 zymogen granule membrane
GO:0046872 metal ion binding
GO:0071456 cellular response to hypoxia

Subcellular Location

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Subcellular Location
Cell membrane
Secreted

Domains

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DomainNameCategoryType
IPR002035 von Willebrand factor, type ADomainDomain
IPR004727 Calcium-activated chloride channel protein, chordataFamilyFamily
IPR013642 Calcium-activated chloride channel, N-terminalDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036465 von Willebrand factor A-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CLCA1_HUMANKCMB1_HUMANBioGRID, HPRD11994272 details
CLCA1_HUMANITB4_HUMANHPRD12110680 14512419 details