Entity Details

Primary name BCL3
Entity type gene
Source Source Link

Details

PrimaryID602
RefseqGeneNG_052809
SymbolBCL3
NameBCL3 transcription coactivator
Chromosome19
Location19q13.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1993-11-10
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsBCL3_HUMAN

GO terms

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GOName
GO:0002268 follicular dendritic cell differentiation
GO:0002315 marginal zone B cell differentiation
GO:0002455 humoral immune response mediated by circulating immunoglobulin
GO:0002467 germinal center formation
GO:0003713 transcription coactivator activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006351 transcription, DNA-templated
GO:0006974 cellular response to DNA damage stimulus
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0008134 transcription factor binding
GO:0009615 response to virus
GO:0010225 response to UV-C
GO:0019730 antimicrobial humoral response
GO:0030198 extracellular matrix organization
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0030496 midbody
GO:0030674 protein-macromolecule adaptor activity
GO:0032717 negative regulation of interleukin-8 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0032729 positive regulation of interferon-gamma production
GO:0032733 positive regulation of interleukin-10 production
GO:0032991 protein-containing complex
GO:0032996 Bcl3-Bcl10 complex
GO:0033257 Bcl3/NF-kappaB2 complex
GO:0042088 T-helper 1 type immune response
GO:0042742 defense response to bacterium
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042832 defense response to protozoan
GO:0042981 regulation of apoptotic process
GO:0043066 negative regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0045064 T-helper 2 cell differentiation
GO:0045727 positive regulation of translation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT
GO:0048471 perinuclear region of cytoplasm
GO:0048536 spleen development
GO:0051101 regulation of DNA binding
GO:0051457 maintenance of protein location in nucleus
GO:1901222 regulation of NIK/NF-kappaB signaling

Diseases

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Interactions

56 interactions

InteractorPartnerSourcesPublicationsLink
BCL3FYNBioGRID, HPRD, MINT16099425 9576921 details
BCL3CTBP2BioGRID, IntAct20547759 21988832 details
BCL3ANKRD28BioGRID, IntAct23414517 details
BCL3PIRBioGRID, MINT10362352 25680527 details
BCL3NFKB2BioGRID, HPRD, IntAct11707390 14678988 17962807 20558726 20800578 28689659 30833792 8453667 details
BCL3NFKB1BioGRID, HPRD, IntAct10362352 10469655 14678988 15829968 17962807 20547759 20558726 20800578 30833792 8428580 details
BCL3NUP58IntAct32814053 details
BCL3BARD1BioGRID, HPRD10362352 details
BCL3N4BP2BioGRID, HPRD12730195 details
BCL3KAT5BioGRID, HPRD10362352 15829968 details
BCL3COPS5BioGRID, HPRD10362352 details
BCL3JUNBioGRID, HPRD10497212 details
BCL3FOSBioGRID, HPRD10497212 details
BCL3EP300BioGRID10497212 details
BCL3NCOA1BioGRID, HPRD10497212 details
BCL3TBPBioGRID, HPRD9812988 details
BCL3RXRABioGRID, HPRD9812988 details
BCL3GTF2A1BioGRID, HPRD9812988 details
BCL3GTF2BBioGRID, HPRD9812988 details
BCL3CTBP1BioGRID20547759 20800578 details
BCL3GSK3BBioGRID, HPRD15469820 details
BCL3MAPRE1BioGRID24552808 details
BCL3AKT1BioGRID28689659 details
BCL3CHUKBioGRID28689659 details
BCL3MAPK1BioGRID28689659 details
BCL3TRAF6BioGRID29933112 details
BCL3BCL10BioGRID, IntAct16280327 details
BCL3LCKMINT16099425 details
BCL3RELBBioGRID14678988 details
BCL3CYLDBioGRID19893491 details
BCL3STAT1BioGRID16306601 details
BCL3STAT3BioGRID16306601 details
BCL3HDAC1BioGRID, HPRD15469820 16306601 details
BCL3HSPA4BioGRID20547759 details
BCL3TBL1XR1BioGRID20547759 details
BCL3BAG2BioGRID20547759 details
BCL3HDAC3BioGRID, HPRD15469820 20547759 details
BCL3RCOR1BioGRID20547759 details
BCL3KDM1ABioGRID20547759 details
BCL3HDAC6BioGRID, HPRD15469820 details
BCL3PSMB1BioGRID20558726 details
BCL3FBXW8BioGRID20558726 details
BCL3CTNNB1BioGRID, HPRD15829968 details
BCL3RUVBL2BioGRID, HPRD15829968 20800578 details
BCL3ESR1BioGRID16331275 details
BCL3RAB9AHPRD11485202 11707390 details
BCL3CREBBPHPRD10497212 details
BCL3SHC1HPRD11707390 details
BCL3GSK3AHPRD15469820 details
BCL3MAPK3HPRD15469820 details
BCL3HSPH1BioGRID, IntAct30833792 details
BCL3HSPA6BioGRID, IntAct30833792 details
BCL3RUVBL1BioGRID20800578 details
BCL3RNF123BioGRID29676528 details
BCL3CUL4ABioGRID30945288 details
BCL3PRC1BioGRID31586073 details