Entity Details

Primary name TAL1
Entity type gene
Source Source Link

Details

PrimaryID6886
RefseqGene
SymbolTAL1
NameTAL bHLH transcription factor 1, erythroid differentiation factor
Chromosome1
Location1p33
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTAL1_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001525 angiogenesis
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0007626 locomotory behavior
GO:0019899 enzyme binding
GO:0021527 spinal cord association neuron differentiation
GO:0030097 hemopoiesis
GO:0030218 erythrocyte differentiation
GO:0030219 megakaryocyte differentiation
GO:0030220 platelet formation
GO:0030221 basophil differentiation
GO:0031334 positive regulation of protein-containing complex assembly
GO:0035162 embryonic hemopoiesis
GO:0035855 megakaryocyte development
GO:0042127 regulation of cell population proliferation
GO:0042826 histone deacetylase binding
GO:0043249 erythrocyte maturation
GO:0045165 cell fate commitment
GO:0045648 positive regulation of erythrocyte differentiation
GO:0045799 positive regulation of chromatin assembly or disassembly
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045931 positive regulation of mitotic cell cycle
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046983 protein dimerization activity
GO:0051781 positive regulation of cell division
GO:0060018 astrocyte fate commitment
GO:0060216 definitive hemopoiesis
GO:0060217 hemangioblast cell differentiation
GO:0060218 hematopoietic stem cell differentiation
GO:0060375 regulation of mast cell differentiation
GO:0070888 E-box binding
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:2000036 regulation of stem cell population maintenance

Diseases

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Interactions

55 interactions

InteractorPartnerSourcesPublicationsLink
TAL1CRKIntAct17474147 details
TAL1DRG1BioGRID, HPRD, IntAct9824680 details
TAL1TCF3BioGRID, DIP, HPRD, IntAct, MINT16407974 19497860 21179004 7568177 8159721 9507011 9824680 details
TAL1TCF4BioGRID, IntAct16407974 8576241 9242638 9824680 details
TAL1TCF12BioGRID, DIP, IntAct, MINT16407974 19497860 21179004 9824680 details
TAL1GATA2BioGRID, IntAct7568177 details
TAL1HOXB9BioGRID, IntAct21988832 details
TAL1CBFA2T3BioGRID, DIP16407974 19497860 26593974 details
TAL1KDM1ABioGRID, DIP19497860 details
TAL1CHD3BioGRID, DIP, HPRD15383276 19497860 details
TAL1LMO2BioGRID, HPRD16407974 7568177 7957052 8078932 9209374 details
TAL1NCAPG2BioGRID, HPRD14729962 details
TAL1EP300BioGRID, HPRD10490830 11118214 11756538 details
TAL1LMO1BioGRID, HPRD7957052 8078932 details
TAL1PRKCQBioGRID10383400 details
TAL1GATA1BioGRID16407974 7568177 details
TAL1SP1BioGRID, HPRD12239153 details
TAL1SIN3ABioGRID, HPRD10688671 11118214 details
TAL1ZHX1BioGRID, HPRD15383276 details
TAL1KAT2BBioGRID, HPRD11118214 details
TAL1ELSPBP1BioGRID, HPRD11118214 8159721 details
TAL1RUNX1BioGRID, DIP, MINT19497860 21179004 details
TAL1ETS1MINT21179004 details
TAL1GATA3BioGRID, HPRD, MINT21179004 9819382 details
TAL1SSBP3BioGRID, DIP16407974 19497860 details
TAL1SSBP2BioGRID, DIP16407974 19497860 details
TAL1LDB1BioGRID, DIP16407974 19497860 details
TAL1HDAC2BioGRID, DIP16407974 19497860 details
TAL1HDAC1BioGRID, DIP, HPRD10688671 16407974 19497860 details
TAL1RB1BioGRID, DIP10866689 19497860 details
TAL1MYBDIP25394790 details
TAL1SSBP1BioGRID16407974 details
TAL1CBFA2T2BioGRID16407974 details
TAL1TRRAPBioGRID16407974 details
TAL1BRD1BioGRID16407974 details
TAL1RCC1BioGRID16407974 details
TAL1XRCC6BioGRID16407974 details
TAL1TOP1BioGRID16407974 details
TAL1PARP1BioGRID16407974 details
TAL1SKP2BioGRID, HPRD17962192 details
TAL1STUB1BioGRID, HPRD17962192 19406989 details
TAL1TRIM27BioGRID16007160 details
TAL1SUV39H1BioGRID15677454 details
TAL1SATB1BioGRID15677454 details
TAL1TAL1BioGRID20603019 details
TAL1MAPK3HPRD8423803 details
TAL1TRIM33BioGRID, IntAct20603019 details
TAL1SUPT16HBioGRID, IntAct20603019 details
TAL1CDK9BioGRID, IntAct20603019 details
TAL1RCOR1BioGRID, DIP19497860 details
TAL1LYL1BioGRID, DIP19497860 details
TAL1BCL11BDIP19497860 details
TAL1CHD4BioGRID, DIP19497860 details
TAL1RBBP7BioGRID, DIP19497860 details
TAL1IRF2BP2BioGRID26593974 details