Entity Details

Primary name APH1B
Entity type gene
Source Source Link

Details

PrimaryID83464
RefseqGene
SymbolAPH1B
Nameaph-1 homolog B, gamma-secretase subunit
Chromosome15
Location15q22.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsAPH1B_HUMAN

GO terms

Show/Hide Table
GOName
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0007219 Notch signaling pathway
GO:0007220 Notch receptor processing
GO:0007626 locomotory behavior
GO:0010008 endosome membrane
GO:0010950 positive regulation of endopeptidase activity
GO:0016021 integral component of membrane
GO:0016485 protein processing
GO:0030133 transport vesicle
GO:0030674 protein-macromolecule adaptor activity
GO:0031293 membrane protein intracellular domain proteolysis
GO:0034205 amyloid-beta formation
GO:0035333 Notch receptor processing, ligand-dependent
GO:0042987 amyloid precursor protein catabolic process
GO:0043065 positive regulation of apoptotic process
GO:0048013 ephrin receptor signaling pathway
GO:0061133 endopeptidase activator activity
GO:0070765 gamma-secretase complex
GO:1990000 amyloid fibril formation

Diseases

Show/Hide Table

Interactions

10 interactions