Entity Details

Primary name SPPL2A
Entity type gene
Source Source Link

Details

PrimaryID84888
RefseqGene
SymbolSPPL2A
Namesignal peptide peptidase like 2A
Chromosome15
Location15q21.2
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2001-05-28
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsSPP2A_HUMAN

GO terms

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GOName
GO:0005765 lysosomal membrane
GO:0005770 late endosome
GO:0005886 plasma membrane
GO:0006509 membrane protein ectodomain proteolysis
GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway
GO:0016020 membrane
GO:0030660 Golgi-associated vesicle membrane
GO:0031293 membrane protein intracellular domain proteolysis
GO:0031902 late endosome membrane
GO:0033619 membrane protein proteolysis
GO:0042500 aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 protein homodimerization activity
GO:0043231 intracellular membrane-bounded organelle
GO:0050776 regulation of immune response
GO:0070062 extracellular exosome
GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane

Diseases

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Interactions

6 interactions

InteractorPartnerSourcesPublicationsLink
SPPL2ASGTABioGRID, HPRD, IntAct16189514 25416956 32296183 details
SPPL2ANFKB1BioGRID, IntAct21988832 details
SPPL2AWFS1IntAct32814053 details
SPPL2ATFRCMINT23384347 details
SPPL2ALGALS8BioGRID, IntAct26186194 28514442 details
SPPL2AVIRMABioGRID29507755 details