Entity Details

Primary name ACER2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ5QJU3
EntryNameACER2_HUMAN
FullNameAlkaline ceramidase 2
TaxID9606
Evidenceevidence at protein level
Length275
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesACER2

GO terms

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GOName
GO:0000139 Golgi membrane
GO:0001953 negative regulation of cell-matrix adhesion
GO:0005794 Golgi apparatus
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 cellular response to DNA damage stimulus
GO:0008284 positive regulation of cell population proliferation
GO:0010506 regulation of autophagy
GO:0010942 positive regulation of cell death
GO:0017040 N-acylsphingosine amidohydrolase activity
GO:0030148 sphingolipid biosynthetic process
GO:0030173 integral component of Golgi membrane
GO:0030330 DNA damage response, signal transduction by p53 class mediator
GO:0032526 response to retinoic acid
GO:0033629 negative regulation of cell adhesion mediated by integrin
GO:0035690 cellular response to drug
GO:0042981 regulation of apoptotic process
GO:0046512 sphingosine biosynthetic process
GO:0046514 ceramide catabolic process
GO:0046872 metal ion binding
GO:0071633 dihydroceramidase activity
GO:0090285 negative regulation of protein glycosylation in Golgi
GO:0102121 ceramidase activity

Subcellular Location

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Subcellular Location
Golgi apparatus membrane

Domains

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DomainNameCategoryType
IPR008901 Alkaline ceramidaseFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ACER2_HUMANEM55_HUMANBioGRID, IntAct32296183 details