Entity Details

Primary name PADI2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y2J8
EntryNamePADI2_HUMAN
FullNameProtein-arginine deiminase type-2
TaxID9606
Evidenceevidence at protein level
Length665
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesPADI2

GO terms

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GOName
GO:0004668 protein-arginine deiminase activity
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006325 chromatin organization
GO:0010848 regulation of chromatin disassembly
GO:0018101 protein citrullination
GO:0021762 substantia nigra development
GO:0030331 estrogen receptor binding
GO:0030520 intracellular estrogen receptor signaling pathway
GO:0035327 transcriptionally active chromatin
GO:0035578 azurophil granule lumen
GO:0036413 histone H3-R26 citrullination
GO:0036414 histone citrullination
GO:0042803 protein homodimerization activity
GO:0043312 neutrophil degranulation
GO:0048096 chromatin-mediated maintenance of transcription
GO:0070062 extracellular exosome
GO:0070100 negative regulation of chemokine-mediated signaling pathway
GO:1901624 negative regulation of lymphocyte chemotaxis
GO:1990830 cellular response to leukemia inhibitory factor

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR004303 Protein-arginine deiminaseFamilyFamily
IPR008972 CupredoxinFamilyHomologous superfamily
IPR013530 Protein-arginine deiminase, C-terminalDomainDomain
IPR013732 Protein-arginine deiminase (PAD), N-terminalDomainDomain
IPR013733 Protein-arginine deiminase (PAD), central domainDomainDomain
IPR036556 Protein-arginine deiminase, central domain superfamilyFamilyHomologous superfamily
IPR038685 PAD, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00155 CitrullineDrugbanksmall molecule

Interactions

0 interactions

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