Entity Details
| Primary name |
CA2D2_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q9NY47 |
| EntryName | CA2D2_HUMAN |
| FullName | Voltage-dependent calcium channel subunit alpha-2/delta-2 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 1150 |
| SequenceStatus | complete |
| DateCreated | 2007-09-11 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Membrane |
Domains
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| Domain | Name | Category | Type |
| IPR002035 | von Willebrand factor, type A | Domain | Domain |
| IPR013608 | VWA N-terminal | Domain | Domain |
| IPR013680 | Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region | Domain | Domain |
| IPR036465 | von Willebrand factor A-like domain superfamily | Family | Homologous superfamily |
Diseases
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| Disease ID | Source | Name | Description |
| 618501 | OMIM | Cerebellar atrophy with seizures and variable developmental delay (CASVDD) | An autosomal recessive neurologic disorder characterized by cerebellar ataxia, atrophy of the cerebellar vermis, severe refractory seizures with early onset, and global developmental delay compatible with epileptic encephalopathy in most patients. Disease severity is variable and normal cognitive development has also been reported. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB00153 | Ergocalciferol | Drugbank | small molecule |
| DB00228 | Enflurane | Drugbank | small molecule |
| DB00270 | Isradipine | Drugbank | small molecule |
| DB00421 | Spironolactone | Drugbank | small molecule |
| DB00996 | Gabapentin | Drugbank | small molecule |
| DB01023 | Felodipine | Drugbank | small molecule |
| DB01054 | Nitrendipine | Drugbank | small molecule |
| DB01244 | Bepridil | Drugbank | small molecule |
| DB08872 | Gabapentin enacarbil | Drugbank | small molecule |
| DB11148 | Butamben | Drugbank | small molecule |
| DB13746 | Bioallethrin | Drugbank | small molecule |
Interactions
1 interaction