Entity Details

Primary name ASMT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP46597
EntryNameASMT_HUMAN
FullNameAcetylserotonin O-methyltransferase
TaxID9606
Evidenceevidence at protein level
Length345
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesASMT

GO terms

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GOName
GO:0005829 cytosol
GO:0006412 translation
GO:0008171 O-methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0017096 acetylserotonin O-methyltransferase activity
GO:0019438 aromatic compound biosynthetic process
GO:0030187 melatonin biosynthetic process
GO:0032259 methylation
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046219 indolalkylamine biosynthetic process

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001077 O-methyltransferase domainDomainDomain
IPR016461 O-methyltransferase COMT-typeFamilyFamily
IPR029063 S-adenosyl-L-methionine-dependent methyltransferaseFamilyHomologous superfamily
IPR031725 Acetylserotonin O-methyltransferase, dimerisation domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01065 MelatoninDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ASMT_HUMANASMT_HUMANUniProt22775292 details