Entity Details

Primary name MPO
Entity type gene
Source Source Link

Details

PrimaryID4353
RefseqGeneNG_009629
SymbolMPO
Namemyeloperoxidase
Chromosome17
Location17q22
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1988-08-16
ModificationDate2021-06-20

Ontological Relatives

UniProt IDsPERM_HUMAN

GO terms

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GOName
GO:0001878 response to yeast
GO:0002149 hypochlorous acid biosynthetic process
GO:0002679 respiratory burst involved in defense response
GO:0003682 chromatin binding
GO:0004601 peroxidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005764 lysosome
GO:0006952 defense response
GO:0006979 response to oxidative stress
GO:0007568 aging
GO:0008201 heparin binding
GO:0009612 response to mechanical stimulus
GO:0019430 removal of superoxide radicals
GO:0020037 heme binding
GO:0030141 secretory granule
GO:0032094 response to food
GO:0032496 response to lipopolysaccharide
GO:0034374 low-density lipoprotein particle remodeling
GO:0035578 azurophil granule lumen
GO:0042582 azurophil granule
GO:0042742 defense response to bacterium
GO:0042744 hydrogen peroxide catabolic process
GO:0043066 negative regulation of apoptotic process
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0045454 cell redox homeostasis
GO:0046872 metal ion binding
GO:0050832 defense response to fungus
GO:0070062 extracellular exosome
GO:0097013 phagocytic vesicle lumen
GO:1990268 response to gold nanoparticle

Diseases

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Disease IDSourceNameDescription
254600 OMIMMyeloperoxidase deficiency (MPOD)A disorder characterized by decreased myeloperoxidase activity in neutrophils and monocytes that results in disseminated candidiasis. The disease is caused by variants affecting the gene represented in this entry.