Entity Details

Primary name LRTOMT
Entity type gene
Source Source Link

Details

PrimaryID220074
RefseqGeneNG_021423
SymbolLRTOMT
Nameleucine rich transmembrane and O-methyltransferase domain containing
Chromosome11
Location11q13.4
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2002-05-05
ModificationDate2021-06-11

Ontological Relatives

GO terms

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GOName
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0007605 sensory perception of sound
GO:0008171 O-methyltransferase activity
GO:0016021 integral component of membrane
GO:0016206 catechol O-methyltransferase activity
GO:0032259 methylation
GO:0032502 developmental process
GO:0042135 neurotransmitter catabolic process
GO:0042417 dopamine metabolic process
GO:0042424 catecholamine catabolic process
GO:0060117 auditory receptor cell development
GO:0102084 L-dopa O-methyltransferase activity
GO:0102938 orcinol O-methyltransferase activity

Diseases

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Disease IDSourceNameDescription
611451 OMIMDeafness, autosomal recessive, 63 (DFNB63)A form of non-syndromic sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. The disease is caused by variants affecting the gene represented in this entry.

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
LRTOMTJOSD2BioGRID, IntAct28514442 details
LRTOMTELAVL1BioGRID19322201 details
LRTOMTHNRNPH1BioGRID26760575 details