Entity Details

Primary name NCLX_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ6J4K2
EntryNameNCLX_HUMAN
FullNameMitochondrial sodium/calcium exchanger protein
TaxID9606
Evidenceevidence at protein level
Length584
SequenceStatuscomplete
DateCreated2006-01-10
DateModified2021-06-02

Ontological Relatives

GenesSLC8B1

GO terms

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GOName
GO:0005432 calcium:sodium antiporter activity
GO:0005743 mitochondrial inner membrane
GO:0005886 plasma membrane
GO:0006811 ion transport
GO:0006812 cation transport
GO:0006851 mitochondrial calcium ion transmembrane transport
GO:0006874 cellular calcium ion homeostasis
GO:0008324 cation transmembrane transporter activity
GO:0016020 membrane
GO:0030061 mitochondrial crista
GO:0032592 integral component of mitochondrial membrane
GO:0042593 glucose homeostasis
GO:0042803 protein homodimerization activity
GO:0050796 regulation of insulin secretion
GO:0050896 response to stimulus
GO:0051480 regulation of cytosolic calcium ion concentration
GO:0051560 mitochondrial calcium ion homeostasis
GO:0086036 regulation of cardiac muscle cell membrane potential
GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential
GO:0099093 calcium export from the mitochondrion
GO:1901623 regulation of lymphocyte chemotaxis
GO:2001256 regulation of store-operated calcium entry

Subcellular Location

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Subcellular Location
Mitochondrion inner membrane

Domains

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DomainNameCategoryType
IPR004837 Sodium/calcium exchanger membrane regionDomainDomain

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink