Entity Details

Primary name DTX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86UW9
EntryNameDTX2_HUMAN
FullNameProbable E3 ubiquitin-protein ligase DTX2
TaxID9606
Evidenceevidence at protein level
Length622
SequenceStatuscomplete
DateCreated2003-09-26
DateModified2021-06-02

Ontological Relatives

GenesDTX2

GO terms

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GOName
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0007219 Notch signaling pathway
GO:0008270 zinc ion binding
GO:0016567 protein ubiquitination
GO:0031965 nuclear membrane
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR004170 WWE domainDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR018123 WWE domain, subgroupDomainDomain
IPR018957 Zinc finger, C3HC4 RING-typeDomainDomain
IPR037197 WWE domain superfamilyFamilyHomologous superfamily
IPR039396 Deltex, C-terminalDomainDomain
IPR039398 Deltex familyFamilyFamily
IPR039399 Deltex, C-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

138 interactions

InteractorPartnerSourcesPublicationsLink
DTX2_HUMANUB2D4_HUMANBioGRID, HPRD, IntAct16189514 19549727 25416956 31515488 32296183 details
DTX2_HUMANRBPMS_HUMANBioGRID, HPRD, IntAct16189514 25416956 details
DTX2_HUMANVISL1_HUMANBioGRID, HPRD, IntAct16189514 25416956 32296183 details
DTX2_HUMANPLS1_HUMANBioGRID, HPRD, IntAct16189514 details
DTX2_HUMANRHXF2_HUMANBioGRID, HPRD, IntAct16189514 details
DTX2_HUMANHPCL4_HUMANBioGRID, HPRD, IntAct16189514 25416956 32296183 details
DTX2_HUMANNCS1_HUMANBioGRID, HPRD, IntAct, MINT16189514 21516116 25416956 32296183 details
DTX2_HUMANRFX6_HUMANBioGRID, HPRD, IntAct16189514 25416956 details
DTX2_HUMANPCH2_HUMANBioGRID, HPRD, IntAct16189514 details
DTX2_HUMANHPCL1_HUMANBioGRID, HPRD, IntAct16189514 32296183 details
DTX2_HUMANNCALD_HUMANBioGRID, HPRD, IntAct, MINT16189514 21516116 25416956 details
DTX2_HUMANUBQL4_HUMANBioGRID, HPRD, IntAct16713569 details
DTX2_HUMANSPG21_HUMANBioGRID, IntAct, MINT21516116 25416956 32296183 details
DTX2_HUMANALKB4_HUMANBioGRID, IntAct, MINT21516116 25416956 31515488 32296183 details
DTX2_HUMANUB2D1_HUMANBioGRID, IntAct, MINT21516116 25416956 32296183 details
DTX2_HUMANSC22A_HUMANBioGRID, IntAct, MINT21516116 25416956 32296183 details
DTX2_HUMAN4ET_HUMANBioGRID, IntAct, MINT21516116 25416956 details
DTX2_HUMANABHGA_HUMANBioGRID, IntAct21516116 25416956 31515488 32296183 details
DTX2_HUMANDCHS_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANSYQ_HUMANBioGRID, IntAct21516116 25416956 details
DTX2_HUMANUB2D3_HUMANBioGRID, IntAct25416956 32296183 details
DTX2_HUMANSC23B_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANF168A_HUMANBioGRID, IntAct25416956 32296183 details
DTX2_HUMANKLC3_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANFHL2_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANRIM3A_HUMANBioGRID, IntAct21516116 25416956 details
DTX2_HUMANTRI54_HUMANBioGRID, IntAct25416956 32296183 details
DTX2_HUMANSUMO1_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANGOGA2_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANTRIP6_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANCA094_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANKR261_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANSPAG8_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANSTX12_HUMANBioGRID, IntAct25416956 31515488 32296183 details
DTX2_HUMANGLCTK_HUMANBioGRID, IntAct25416956 32296183 details
DTX2_HUMANPKHF2_HUMANBioGRID, IntAct25416956 details
DTX2_HUMANDTX2_HUMANBioGRID, HPRD, IntAct11226752 25416956 32937373 details
DTX2_HUMANCCD57_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANLNX1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANHSFY1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANARMC7_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANHXB2_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANPRR32_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANPKHG4_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANPAX5_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANUBP54_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKANK2_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANHPCA_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANUB2D2_HUMANBioGRID, IntAct32296183 32937373 details
DTX2_HUMANSC23A_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANIKZF3_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANCS054_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANFHL5_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKR196_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANFCRL4_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANMSS51_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANGLD2_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANTBX15_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKLD7B_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANTMM42_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANCT085_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANCK001_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANHLX_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANANKMT_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANECM1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANCV039_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANBWR1B_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANTRIB3_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANLR2BP_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKR133_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANRBM11_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANNIF3L_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANMXRA8_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANHXD12_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANMVP_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANCOA6_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANCLPP_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKR197_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANPSB4_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANTEKT5_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANZN774_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANTRI35_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANBICRL_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANHXA1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANSPCS_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANHGS_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANPRR34_HUMANIntAct32296183 details
DTX2_HUMANARI5A_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANSOLH1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANPOGZ_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANZN503_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANECSIT_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANCJ055_HUMANIntAct32296183 details
DTX2_HUMANVGLL3_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANMS18B_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANB2L11_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKR191_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANRUSC1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANPPR32_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANDAZP2_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANABHDB_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANFOXI1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKR111_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANEYA2_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANMED19_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANFTO_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANLASP1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANMB3L1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANNHLC4_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANZN764_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANIF4G1_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANAPC11_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANZN620_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKRA81_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANNDKM_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKR151_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANDOK3_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKRA61_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANKRA71_HUMANBioGRID, IntAct32296183 details
DTX2_HUMANCOQ8A_HUMANBioGRID, IntAct25910212 details
DTX2_HUMANMDC1_HUMANBioGRID22990118 details
DTX2_HUMANARNT2_HUMANBioGRID24722188 32296183 details
DTX2_HUMANZN641_HUMANBioGRID21516116 details
DTX2_HUMANRUNX1_HUMANBioGRID28536267 details
DTX2_HUMANZNF85_HUMANBioGRID32296183 details
DTX2_HUMANZNF34_HUMANBioGRID32296183 details
DTX2_HUMANPARP1_HUMANBioGRID32937373 details
DTX2_HUMANH31_HUMANBioGRID32937373 details
DTX2_HUMANNOTC1_HUMANHPRD11226752 details
DTX2_HUMANDTX1_HUMANHPRD11226752 details
DTX2_HUMANDTX3_HUMANHPRD11226752 details
DTX2_HUMAN1433S_HUMANBioGRID, MINT15778465 details
DTX2_HUMANH4_HUMANBioGRID, IntAct30021884 details
DTX2_HUMANSP16H_HUMANBioGRID32937373 details
DTX2_HUMANSSRP1_HUMANBioGRID32937373 details
DTX2_HUMANXRCC5_HUMANBioGRID32937373 details
DTX2_HUMANXRCC6_HUMANBioGRID32937373 details
DTX2_HUMANRFA1_HUMANBioGRID32937373 details