Entity Details

Primary name TMPSC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ86WS5
EntryNameTMPSC_HUMAN
FullNameTransmembrane protease serine 12
TaxID9606
Evidenceevidence at protein level
Length348
SequenceStatuscomplete
DateCreated2007-06-12
DateModified2021-06-02

Ontological Relatives

GenesTMPRSS12

GO terms

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GOName
GO:0001669 acrosomal vesicle
GO:0004252 serine-type endopeptidase activity
GO:0007339 binding of sperm to zona pellucida
GO:0016021 integral component of membrane
GO:0016485 protein processing

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
TMPSC_HUMANBRCA1_HUMANBioGRID25184681 details