Entity Details

Primary name RTKN2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8IZC4
EntryNameRTKN2_HUMAN
FullNameRhotekin-2
TaxID9606
Evidenceevidence at transcript level
Length609
SequenceStatuscomplete
DateCreated2007-11-13
DateModified2021-06-02

Ontological Relatives

GenesRTKN2

GO terms

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GOName
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0007165 signal transduction
GO:0008284 positive regulation of cell population proliferation
GO:0030097 hemopoiesis
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001849 Pleckstrin homology domainDomainDomain
IPR011072 HR1 rho-binding domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR012966 Anillin homology domainDomainDomain
IPR030469 Rhotekin-2FamilyFamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
RTKN2_HUMANPACN1_HUMANBioGRID, IntAct20936779 details
RTKN2_HUMANBRCA1_HUMANBioGRID22990118 details
RTKN2_HUMANEST1A_HUMANBioGRID29395067 details