Entity Details

Primary name AF1L2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8N4X5
EntryNameAF1L2_HUMAN
FullNameActin filament-associated protein 1-like 2
TaxID9606
Evidenceevidence at protein level
Length818
SequenceStatuscomplete
DateCreated2005-06-21
DateModified2021-06-02

Ontological Relatives

GenesAFAP1L2

GO terms

Show/Hide Table
GOName
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006954 inflammatory response
GO:0007346 regulation of mitotic cell cycle
GO:0017124 SH3 domain binding
GO:0030296 protein tyrosine kinase activator activity
GO:0032675 regulation of interleukin-6 production
GO:0032757 positive regulation of interleukin-8 production
GO:0035591 signaling adaptor activity
GO:0042169 SH2 domain binding
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR030113 Actin-filament associated proteinFamilyFamily
IPR030115 Actin filament-associated protein 1-like 2FamilyFamily

Diseases

Show/Hide Table