Entity Details

Primary name RN149_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NC42
EntryNameRN149_HUMAN
FullNameE3 ubiquitin-protein ligase RNF149
TaxID9606
Evidenceevidence at transcript level
Length400
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesRNF149

GO terms

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GOName
GO:0005737 cytoplasm
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031647 regulation of protein stability
GO:0035690 cellular response to drug
GO:0043409 negative regulation of MAPK cascade
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR003137 PA domainDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR042712 E3 ubiquitin-protein ligase RNF149, RING finger, H2 subclassDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
RN149_HUMANBRAF_HUMANBioGRID22628551 details