Entity Details

Primary name ACV1C_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8NER5
EntryNameACV1C_HUMAN
FullNameActivin receptor type-1C
TaxID9606
Evidenceevidence at protein level
Length493
SequenceStatuscomplete
DateCreated2005-10-25
DateModified2021-06-02

Ontological Relatives

GenesACVR1C

GO terms

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GOName
GO:0001834 trophectodermal cell proliferation
GO:0002021 response to dietary excess
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0007399 nervous system development
GO:0009749 response to glucose
GO:0016361 activin receptor activity, type I
GO:0019838 growth factor binding
GO:0019915 lipid storage
GO:0030154 cell differentiation
GO:0030262 apoptotic nuclear changes
GO:0032868 response to insulin
GO:0032924 activin receptor signaling pathway
GO:0038092 nodal signaling pathway
GO:0038100 nodal binding
GO:0043065 positive regulation of apoptotic process
GO:0043235 receptor complex
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0046676 negative regulation of insulin secretion
GO:0046872 metal ion binding
GO:0048179 activin receptor complex
GO:0071363 cellular response to growth factor stimulus
GO:1901164 negative regulation of trophoblast cell migration
GO:1901383 negative regulation of chorionic trophoblast cell proliferation

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000333 Ser/Thr protein kinase, TGFB receptorFamilyFamily
IPR000472 Activin types I and II receptor domainDomainDomain
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR003605 GS domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site

Diseases

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Interactions

4 interactions