Entity Details

Primary name S22A8_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TCC7
EntryNameS22A8_HUMAN
FullNameSolute carrier family 22 member 8
TaxID9606
Evidenceevidence at protein level
Length542
SequenceStatuscomplete
DateCreated2007-01-23
DateModified2021-06-02

Ontological Relatives

GenesSLC22A8

GO terms

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GOName
GO:0005452 inorganic anion exchanger activity
GO:0005886 plasma membrane
GO:0009636 response to toxic substance
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular exosome
GO:0150104 transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Basolateral cell membrane

Domains

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DomainNameCategoryType
IPR004749 Organic cation transport protein/SVOPFamilyFamily
IPR005828 Major facilitator, sugar transporter-likeFamilyFamily
IPR005829 Sugar transporter, conserved siteSiteConserved site
IPR020846 Major facilitator superfamily domainDomainDomain
IPR036259 MFS transporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00139 Succinic acidDrugbanksmall molecule
DB00168 AspartameDrugbanksmall molecule
DB00175 PravastatinDrugbanksmall molecule
DB00198 OseltamivirDrugbanksmall molecule
DB00213 PantoprazoleDrugbanksmall molecule
DB00229 CefotiamDrugbanksmall molecule
DB00253 MedrysoneDrugbanksmall molecule
DB00279 LiothyronineDrugbanksmall molecule
DB00286 Conjugated estrogensDrugbanksmall molecule
DB00300 Tenofovir disoproxilDrugbanksmall molecule
DB00313 Valproic acidDrugbanksmall molecule
DB00319 PiperacillinDrugbanksmall molecule
DB00328 IndomethacinDrugbanksmall molecule
DB00345 Aminohippuric acidSwissprotsmall molecule
DB00437 AllopurinolDrugbanksmall molecule
DB00448 LansoprazoleDrugbanksmall molecule
DB00456 CefalotinDrugbanksmall molecule
DB00469 TenoxicamDrugbanksmall molecule
DB00493 CefotaximeDrugbanksmall molecule
DB00495 ZidovudineDrugbanksmall molecule
DB00501 CimetidineDrugbanksmall molecule
DB00535 CefdinirDrugbanksmall molecule
DB00536 GuanidineDrugbanksmall molecule
DB00554 PiroxicamDrugbanksmall molecule
DB00563 MethotrexateDrugbanksmall molecule
DB00567 CephalexinDrugbanksmall molecule
DB00577 ValaciclovirDrugbanksmall molecule
DB00583 LevocarnitineDrugbanksmall molecule
DB00584 EnalaprilDrugbanksmall molecule
DB00586 DiclofenacDrugbanksmall molecule
DB00595 OxytetracyclineDrugbanksmall molecule
DB00624 TestosteroneDrugbanksmall molecule
DB00642 PemetrexedDrugbanksmall molecule
DB00650 LeucovorinSwissprotsmall molecule
DB00654 LatanoprostDrugbanksmall molecule
DB00655 EstroneDrugbanksmall molecule
DB00695 FurosemideDrugbanksmall molecule
DB00736 EsomeprazoleDrugbanksmall molecule
DB00741 HydrocortisoneDrugbanksmall molecule
DB00759 TetracyclineDrugbanksmall molecule
DB00774 HydroflumethiazideDrugbanksmall molecule
DB00783 EstradiolDrugbanksmall molecule
DB00787 AcyclovirDrugbanksmall molecule
DB00788 NaproxenDrugbanksmall molecule
DB00812 PhenylbutazoneDrugbanksmall molecule
DB00833 CefaclorDrugbanksmall molecule
DB00863 RanitidineDrugbanksmall molecule
DB00881 QuinaprilDrugbanksmall molecule
DB00887 BumetanideDrugbanksmall molecule
DB00908 QuinidineDrugbanksmall molecule
DB00917 DinoprostoneDrugbanksmall molecule
DB00927 FamotidineDrugbanksmall molecule
DB00936 Salicylic acidDrugbanksmall molecule
DB00945 Acetylsalicylic acidDrugbanksmall molecule
DB00950 FexofenadineDrugbanksmall molecule
DB00999 HydrochlorothiazideDrugbanksmall molecule
DB01004 GanciclovirDrugbanksmall molecule
DB01009 KetoprofenDrugbanksmall molecule
DB01032 ProbenecidDrugbanksmall molecule
DB01033 MercaptopurineDrugbanksmall molecule
DB01045 RifampicinDrugbanksmall molecule
DB01050 IbuprofenDrugbanksmall molecule
DB01051 NovobiocinDrugbanksmall molecule
DB01053 BenzylpenicillinDrugbanksmall molecule
DB01065 MelatoninDrugbanksmall molecule
DB01092 OuabainDrugbanksmall molecule
DB01098 RosuvastatinDrugbanksmall molecule
DB01140 CefadroxilDrugbanksmall molecule
DB01160 Dinoprost tromethamineDrugbanksmall molecule
DB01212 CeftriaxoneDrugbanksmall molecule
DB01222 BudesonideDrugbanksmall molecule
DB01234 DexamethasoneDrugbanksmall molecule
DB01241 GemfibrozilDrugbanksmall molecule
DB01261 SitagliptinDrugbanksmall molecule
DB01324 PolythiazideDrugbanksmall molecule
DB01326 CefamandoleDrugbanksmall molecule
DB01327 CefazolinDrugbanksmall molecule
DB01329 CefoperazoneDrugbanksmall molecule
DB01332 CeftizoximeDrugbanksmall molecule
DB01414 CefacetrileDrugbanksmall molecule
DB01415 CeftibutenDrugbanksmall molecule
DB01583 LiotrixDrugbanksmall molecule
DB01597 CilastatinDrugbanksmall molecule
DB01606 TazobactamDrugbanksmall molecule
DB01650 trans-2-hydroxycinnamic acidDrugbanksmall molecule
DB01685 TopiroxostatDrugbanksmall molecule
DB02527 Cyclic adenosine monophosphateDrugbanksmall molecule
DB02659 Cholic AcidDrugbanksmall molecule
DB03553 Glutaric AcidDrugbanksmall molecule
DB03793 Benzoic acidDrugbanksmall molecule
DB03902 Oxalic AcidDrugbanksmall molecule
DB04133 Degraded CephaloridineDrugbanksmall molecule
DB04348 Taurocholic acidDrugbanksmall molecule
DB04519 Caprylic acidDrugbanksmall molecule
DB04855 DronedaroneDrugbanksmall molecule
DB05016 AtalurenSwissprotsmall molecule
DB05154 PretomanidDrugbanksmall molecule
DB05804 Prasterone sulfateSwissprotsmall molecule
DB06211 DoripenemDrugbanksmall molecule
DB06335 SaxagliptinDrugbanksmall molecule
DB06710 MethyltestosteroneDrugbanksmall molecule
DB08837 TetraethylammoniumDrugbanksmall molecule
DB08844 Uric acidSwissprotsmall molecule
DB08912 DabrafenibDrugbanksmall molecule
DB08930 DolutegravirDrugbanksmall molecule
DB09008 CefaloridineSwissprotsmall molecule
DB09038 EmpagliflozinDrugbanksmall molecule
DB09060 AvibactamDrugbanksmall molecule
DB09078 LenvatinibDrugbanksmall molecule
DB09213 DexibuprofenDrugbanksmall molecule
DB09272 EluxadolineDrugbanksmall molecule
DB09274 ArtesunateDrugbanksmall molecule
DB09299 Tenofovir alafenamideDrugbanksmall molecule
DB11644 TafamidisDrugbanksmall molecule
DB11751 CabotegravirSwissprotsmall molecule
DB11817 BaricitinibDrugbanksmall molecule
DB11837 OsilodrostatDrugbanksmall molecule
DB11901 ApalutamideDrugbanksmall molecule
DB11995 AvatrombopagDrugbanksmall molecule
DB12070 LetermovirDrugbanksmall molecule
DB12243 EdaravoneSwissprotsmall molecule
DB12332 RucaparibDrugbanksmall molecule
DB12377 RelebactamDrugbanksmall molecule
DB12457 RimegepantDrugbanksmall molecule
DB12466 FavipiravirDrugbanksmall molecule
DB12866 PradigastatSwissprotsmall molecule
DB13874 EnasidenibDrugbanksmall molecule
DB13943 Testosterone cypionateDrugbanksmall molecule
DB13944 Testosterone enanthateDrugbanksmall molecule
DB13946 Testosterone undecanoateDrugbanksmall molecule
DB13952 Estradiol acetateDrugbanksmall molecule
DB13953 Estradiol benzoateDrugbanksmall molecule
DB13954 Estradiol cypionateDrugbanksmall molecule
DB13955 Estradiol dienanthateDrugbanksmall molecule
DB13956 Estradiol valerateDrugbanksmall molecule
DB14126 TenofovirDrugbanksmall molecule
DB14538 Hydrocortisone aceponateDrugbanksmall molecule
DB14539 Hydrocortisone acetateDrugbanksmall molecule
DB14540 Hydrocortisone butyrateDrugbanksmall molecule
DB14541 Hydrocortisone cypionateDrugbanksmall molecule
DB14542 Hydrocortisone phosphateDrugbanksmall molecule
DB14543 Hydrocortisone probutateDrugbanksmall molecule
DB14544 Hydrocortisone valerateDrugbanksmall molecule
DB14568 IvosidenibDrugbanksmall molecule
DB14631 Prednisolone phosphateDrugbanksmall molecule
DB14649 Dexamethasone acetateDrugbanksmall molecule
DB14669 Betamethasone phosphateDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
S22A8_HUMANNED4L_HUMANBioGRID26651153 details
S22A8_HUMANNEDD4_HUMANBioGRID28608480 details