Entity Details

Primary name ZN675_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TD23
EntryNameZN675_HUMAN
FullNameZinc finger protein 675
TaxID9606
Evidenceevidence at protein level
Length568
SequenceStatuscomplete
DateCreated2007-09-11
DateModified2021-06-02

Ontological Relatives

GenesZNF675

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0008270 zinc ion binding
GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0019221 cytokine-mediated signaling pathway
GO:0031625 ubiquitin protein ligase binding
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0043508 negative regulation of JUN kinase activity
GO:0045453 bone resorption
GO:0045671 negative regulation of osteoclast differentiation
GO:0046329 negative regulation of JNK cascade
GO:0048471 perinuclear region of cytoplasm
GO:2000660 negative regulation of interleukin-1-mediated signaling pathway
GO:2000678 negative regulation of transcription regulatory region DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001909 Krueppel-associated boxDomainDomain
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036051 KRAB domain superfamilyFamilyHomologous superfamily
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ZN675_HUMANTRAF6_HUMANBioGRID, HPRD, IntAct11751921 details
ZN675_HUMANLMO4_HUMANBioGRID, HPRD, MINT15231748 details
ZN675_HUMANHD_HUMANIntAct17500595 details