Entity Details

Primary name TRPM4_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TD43
EntryNameTRPM4_HUMAN
FullNameTransient receptor potential cation channel subfamily M member 4
TaxID9606
Evidenceevidence at protein level
Length1214
SequenceStatuscomplete
DateCreated2006-10-31
DateModified2021-06-02

Ontological Relatives

GenesTRPM4

GO terms

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GOName
GO:0002250 adaptive immune response
GO:0002407 dendritic cell chemotaxis
GO:0002724 regulation of T cell cytokine production
GO:0005227 calcium activated cation channel activity
GO:0005261 cation channel activity
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0008284 positive regulation of cell population proliferation
GO:0010460 positive regulation of heart rate
GO:0016925 protein sumoylation
GO:0019722 calcium-mediated signaling
GO:0030502 negative regulation of bone mineralization
GO:0034706 sodium channel complex
GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0042310 vasoconstriction
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0044214 spanning component of plasma membrane
GO:0045600 positive regulation of fat cell differentiation
GO:0045668 negative regulation of osteoblast differentiation
GO:0045907 positive regulation of vasoconstriction
GO:0051289 protein homotetramerization
GO:0070588 calcium ion transmembrane transport
GO:0071318 cellular response to ATP
GO:0086045 membrane depolarization during AV node cell action potential
GO:0086047 membrane depolarization during Purkinje myocyte cell action potential
GO:0086048 membrane depolarization during bundle of His cell action potential
GO:0086091 regulation of heart rate by cardiac conduction
GO:0089717 spanning component of membrane
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:0098655 cation transmembrane transport
GO:0098662 inorganic cation transmembrane transport
GO:0098719 sodium ion import across plasma membrane
GO:0098911 regulation of ventricular cardiac muscle cell action potential
GO:0099604 ligand-gated calcium channel activity
GO:1903949 positive regulation of atrial cardiac muscle cell action potential
GO:1904179 positive regulation of adipose tissue development
GO:1904199 positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization

Subcellular Location

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Subcellular Location
Cell membrane
Endoplasmic reticulum
Golgi apparatus

Domains

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DomainNameCategoryType
IPR005821 Ion transport domainDomainDomain
IPR029581 Transient receptor potential cation channel subfamily M member 4FamilyFamily
IPR041491 TRPM, SLOG domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01016 GlyburideDrugbanksmall molecule