Entity Details

Primary name ACER1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8TDN7
EntryNameACER1_HUMAN
FullNameAlkaline ceramidase 1
TaxID9606
Evidenceevidence at protein level
Length264
SequenceStatuscomplete
DateCreated2006-07-25
DateModified2021-06-02

Ontological Relatives

GenesACER1

GO terms

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GOName
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0006665 sphingolipid metabolic process
GO:0008544 epidermis development
GO:0010446 response to alkaline pH
GO:0016021 integral component of membrane
GO:0017040 N-acylsphingosine amidohydrolase activity
GO:0030148 sphingolipid biosynthetic process
GO:0030154 cell differentiation
GO:0030216 keratinocyte differentiation
GO:0046512 sphingosine biosynthetic process
GO:0046514 ceramide catabolic process
GO:0046872 metal ion binding
GO:0071277 cellular response to calcium ion
GO:0071633 dihydroceramidase activity
GO:0102121 ceramidase activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane

Domains

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DomainNameCategoryType
IPR008901 Alkaline ceramidaseFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ACER1_HUMANEM55_HUMANBioGRID, IntAct32296183 details