Entity Details

Primary name PRP31_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WWY3
EntryNamePRP31_HUMAN
FullNameU4/U6 small nuclear ribonucleoprotein Prp31
TaxID9606
Evidenceevidence at protein level
Length499
SequenceStatuscomplete
DateCreated2006-03-21
DateModified2021-06-02

Ontological Relatives

GenesPRPF31

GO terms

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GOName
GO:0000244 spliceosomal tri-snRNP complex assembly
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005684 U2-type spliceosomal complex
GO:0005687 U4 snRNP
GO:0005690 U4atac snRNP
GO:0015030 Cajal body
GO:0016607 nuclear speck
GO:0030621 U4 snRNA binding
GO:0030622 U4atac snRNA binding
GO:0042802 identical protein binding
GO:0043021 ribonucleoprotein complex binding
GO:0046540 U4/U6 x U5 tri-snRNP complex
GO:0070990 snRNP binding
GO:0071005 U2-type precatalytic spliceosome
GO:0071011 precatalytic spliceosome
GO:0071166 ribonucleoprotein complex localization
GO:0071339 MLL1 complex
GO:0097526 spliceosomal tri-snRNP complex

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR002687 Nop domainDomainDomain
IPR012976 NOSICDomainDomain
IPR019175 Prp31 C-terminalDomainDomain
IPR027105 U4/U6 small nuclear ribonucleoprotein Prp31FamilyFamily
IPR029012 Helix hairpin bin domain superfamilyFamilyHomologous superfamily
IPR036070 Nop domain superfamilyFamilyHomologous superfamily
IPR042239 Nop, C-terminal domainFamilyHomologous superfamily

Diseases

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Interactions

177 interactions

InteractorPartnerSourcesPublicationsLink
PRP31_HUMANPRP4_HUMANBioGRID, IntAct16723661 19615732 26344197 26496610 28514442 details
PRP31_HUMANRACK1_HUMANBioGRID, MINT22365833 details
PRP31_HUMANTAD2A_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANRBY1A_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANK1C15_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANKR108_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANMKRN3_HUMANBioGRID, IntAct25416956 25910212 27107012 32296183 details
PRP31_HUMANMTUS2_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANK1C40_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANKHDR2_HUMANBioGRID, IntAct25416956 25910212 27107012 details
PRP31_HUMANSIAH1_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANPNMA1_HUMANBioGRID, IntAct25416956 25910212 27107012 32296183 details
PRP31_HUMANKCTD6_HUMANBioGRID, IntAct25416956 25910212 31515488 32296183 details
PRP31_HUMANTRIM1_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANTRI23_HUMANBioGRID, IntAct30886144 32296183 details
PRP31_HUMANKRA11_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANCAR14_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANCCD70_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANU520_HUMANBioGRID25849387 26344197 details
PRP31_HUMANTRI27_HUMANBioGRID, IntAct25416956 25910212 27107012 details
PRP31_HUMANZN250_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANGOGA2_HUMANBioGRID, IntAct25416956 25910212 27107012 32296183 details
PRP31_HUMANRBY1F_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANLURA1_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANHES7_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANZN408_HUMANBioGRID, IntAct25910212 details
PRP31_HUMANZNF24_HUMANBioGRID, IntAct25910212 details
PRP31_HUMANKR101_HUMANBioGRID25416956 25910212 details
PRP31_HUMANCCD33_HUMANBioGRID25910212 32296183 details
PRP31_HUMANUBP15_HUMANBioGRID, IntAct19615732 28088760 details
PRP31_HUMANHNRPK_HUMANBioGRID, IntAct25416956 25910212 27107012 32296183 details
PRP31_HUMANASPP2_HUMANBioGRID, IntAct25416956 32296183 details
PRP31_HUMANMIPO1_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANCEP70_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANJKIP2_HUMANBioGRID, IntAct25416956 25910212 27107012 details
PRP31_HUMANZN587_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANTSG10_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANMEOX2_HUMANBioGRID, IntAct27107012 details
PRP31_HUMANHSF2B_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANBHLH9_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANRUN3A_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANZN792_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANLHX8_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANUBX11_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANZN668_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANPRPF3_HUMANBioGRID, IntAct16723661 26344197 28514442 details
PRP31_HUMANNT2NA_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANMDFI_HUMANBioGRID, IntAct25910212 27107012 details
PRP31_HUMANREL_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANPP16A_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANP2R3C_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANPRP31_HUMANBioGRID, IntAct16723661 32296183 details
PRP31_HUMANLZTS2_HUMANBioGRID, IntAct25910212 details
PRP31_HUMANPPIP1_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANTFP11_HUMANBioGRID, IntAct25416956 25910212 27107012 31515488 32296183 details
PRP31_HUMANCCDB1_HUMANBioGRID, IntAct27107012 32296183 details
PRP31_HUMANZN837_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANMEIS3_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANFACC1_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANFXR1_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANCC106_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANCCD57_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANPRIC1_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANPNMA2_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANDVL2_HUMANBioGRID, IntAct27107012 details
PRP31_HUMANZN774_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANUSH1G_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANFASTK_HUMANBioGRID, IntAct25910212 details
PRP31_HUMANTRI54_HUMANIntAct30886144 details
PRP31_HUMANNT2NC_HUMANBioGRID25416956 25910212 details
PRP31_HUMANFANCC_HUMANBioGRID24676280 details
PRP31_HUMANRBM4_HUMANBioGRID, MINT22365833 details
PRP31_HUMANKHDR3_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANLDOC1_HUMANBioGRID, IntAct25416956 25910212 31515488 32296183 details
PRP31_HUMANSTX11_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANADIP_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANGG6L9_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANFBLN4_HUMANBioGRID, IntAct25910212 32296183 details
PRP31_HUMANRBAK_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANKR195_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANZF69B_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANCDR2L_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANPHF5A_HUMANBioGRID, MINT22365833 22939629 details
PRP31_HUMANRBMX_HUMANBioGRID, IntAct25910212 32296183 details
PRP31_HUMANTRI14_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANDVL3_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANBICD2_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANVWC2_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANCPNS2_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANNH2L1_HUMANBioGRID16723661 26275778 details
PRP31_HUMANRBM25_HUMANBioGRID, MINT22365833 details
PRP31_HUMANCTBL1_HUMANBioGRID, MINT21385873 24269683 details
PRP31_HUMANTLE5_HUMANBioGRID, IntAct25416956 25910212 27107012 32296183 details
PRP31_HUMANMYOME_HUMANBioGRID, IntAct25416956 25910212 31515488 details
PRP31_HUMANCDA7L_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANC1QT1_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANCBY2_HUMANBioGRID, IntAct27107012 details
PRP31_HUMANPICK1_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANKRT35_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANPKHG4_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANKR109_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANCACO2_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANPHC2_HUMANBioGRID, IntAct25416956 25910212 details
PRP31_HUMANKANK2_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANKIFC3_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANZNF71_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANLBX1_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANSPN90_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANSLAI1_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANFANCA_HUMANBioGRID14499622 details
PRP31_HUMANCC136_HUMANBioGRID, IntAct25416956 25910212 32296183 details
PRP31_HUMANHAP1_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANZSC22_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANKRA13_HUMANBioGRID32296183 details
PRP31_HUMANRINT1_HUMANBioGRID, IntAct27107012 details
PRP31_HUMANK1H1_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANEVI5_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANTRI41_HUMANBioGRID, IntAct25910212 details
PRP31_HUMANKRT34_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANZRAN1_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANHOOK2_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANPRP6_HUMANBioGRID, MINT, UniProt16723661 22365833 22939629 26344197 details
PRP31_HUMANPNMA3_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANPAK5_HUMANBioGRID, IntAct25910212 32296183 details
PRP31_HUMANPRD14_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANTMCC2_HUMANBioGRID25416956 25910212 details
PRP31_HUMANZNF48_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANZN417_HUMANBioGRID, IntAct25910212 details
PRP31_HUMANKR103_HUMANBioGRID25416956 25910212 details
PRP31_HUMANHNRH2_HUMANBioGRID, MINT22365833 details
PRP31_HUMANFSD2_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANHD_HUMANIntAct32814053 details
PRP31_HUMANCRTP1_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANKR411_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANCNDH2_HUMANBioGRID, IntAct25910212 details
PRP31_HUMANPPIH_HUMANBioGRID16723661 details
PRP31_HUMANZN473_HUMANBioGRID, IntAct25910212 details
PRP31_HUMANCDC23_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANASB15_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANZF64B_HUMANBioGRID, IntAct25910212 details
PRP31_HUMANOGT1_HUMANBioGRID32994395 details
PRP31_HUMANSRSF3_HUMANBioGRID, IntAct32296183 details
PRP31_HUMANSMD3_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANSMD1_HUMANBioGRID, IntAct26344197 27173435 unassigned1312 details
PRP31_HUMANOSBL1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANTT21B_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANSMN_HUMANBioGRID26275778 details
PRP31_HUMANTXNIP_HUMANBioGRID31669268 details
PRP31_HUMANSART3_HUMANBioGRID, IntAct19615732 28088760 28514442 details
PRP31_HUMANCSN8_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANGAN_HUMANBioGRID26460568 details
PRP31_HUMANSMC3_HUMANBioGRID31010829 details
PRP31_HUMANRSMB_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANPRP8_HUMANBioGRID26344197 28088760 28515276 details
PRP31_HUMANRUVB1_HUMANBioGRID26275778 details
PRP31_HUMANSTAG1_HUMANBioGRID31010829 details
PRP31_HUMANSMD2_HUMANBioGRID, IntAct26344197 27173435 unassigned1312 details
PRP31_HUMANRUXG_HUMANBioGRID, IntAct27173435 28514442 unassigned1312 details
PRP31_HUMANRANB9_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANUBE2N_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANOLA1_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANLSM2_HUMANBioGRID29395067 details
PRP31_HUMANRAD21_HUMANBioGRID31010829 details
PRP31_HUMANLA_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANCAF1A_HUMANBioGRID21209461 details
PRP31_HUMANWAPL_HUMANBioGRID31010829 details
PRP31_HUMANRS19_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANIMA5_HUMANBioGRID21385873 details
PRP31_HUMANIFT46_HUMANBioGRID, IntAct27173435 unassigned1312 details
PRP31_HUMANZNHI3_HUMANBioGRID26275778 details
PRP31_HUMANCYBP_HUMANBioGRID29806702 details
PRP31_HUMANPDS5A_HUMANBioGRID31010829 details
PRP31_HUMANSTAG2_HUMANBioGRID31010829 details
PRP31_HUMANNIPBL_HUMANBioGRID31010829 details
PRP31_HUMANNUFP1_HUMANBioGRID26275778 details
PRP31_HUMANIMA1_HUMANBioGRID21385873 details
PRP31_HUMANSMC1A_HUMANBioGRID31010829 details