Entity Details

Primary name TOPK_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96KB5
EntryNameTOPK_HUMAN
FullNameLymphokine-activated killer T-cell-originated protein kinase
TaxID9606
Evidenceevidence at protein level
Length322
SequenceStatuscomplete
DateCreated2005-02-01
DateModified2021-06-02

Ontological Relatives

GenesPBK

GO terms

Show/Hide Table
GOName
GO:0000278 mitotic cell cycle
GO:0001933 negative regulation of protein phosphorylation
GO:0004674 protein serine/threonine kinase activity
GO:0004708 MAP kinase kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032873 negative regulation of stress-activated MAPK cascade
GO:0034644 cellular response to UV
GO:0050728 negative regulation of inflammatory response
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity

Subcellular Location

Show/Hide Table

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR041989 TOPK, catalytic domainDomainDomain

Diseases

Show/Hide Table